| 王官峰,陈如.硕通镜治疗上尿路结石的临床疗效及对肾功能的影响:一项随机、对照、开放研究[J].安徽医药,2020,24(12):2457-2459. |
| 硕通镜治疗上尿路结石的临床疗效及对肾功能的影响:一项随机、对照、开放研究 |
| Clinical efficacy of Shuotong Jing in the treatment of upper urinary calculi and its effect on renal function:a randomized control open?label clinical trial |
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| DOI：10.3969/j.issn.1009?6469.2020.12.031 |
| 中文关键词: 尿路结石 碎石术，激光 硕通镜 钬激光 输尿管镜检查 碎石术 |
| 英文关键词: Urinary calculi Lithotripsy,laser Shuotong Jing Holmium laser Ureteroscopy Lithotripsy |
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| 中文摘要: |
| 目的评价硕通镜治疗上尿路结石的临床疗效及对肾功能的影响。方法 2018年 1月至 2019年 4月，三二〇一医院收治的 80例单侧上尿路结石的病人入选，采用随机数字表法分为两组(n＝40):硕通镜组(S组)和输尿管软镜组(C组)比较两组病人的手术时间、结石清除率、并发症发生率(感染、发热、血尿、输尿管黏膜损伤)、术前术后尿液中 α1微球蛋白和血清，胱抑素 C的水平。结果 C组手术时间为(59±10)min，结石清除率为 82.5%，并发症发生率为 20%，而 S组手术时间为(36±9)min，结石清除率为 97.5%，并发症发生率为 2.5%；术后 12 h和术后 24 h两组病人 α1微球蛋白为 C组(9.33±1.03)mg/L比 S组(5.06±1.02)mg/L和 C组(13.05±1.09)mg/L比 S组(7.19±0.96)mg/L；术后 12 h和术后 24 h两组病人血清胱抑素 C为 C组(1.33±0.38) mg/L比 S组(0.92±0.31)mg/L和 C组(1.62±0.66)mg/L比 S组(1.26±0.40)mg/L，以上各项指标两组比较均差异有统计学意义(P＜0.05)。结论治疗上尿路结石，硕通镜碎石术较输尿管软镜所需手术时间短，结石清除率高，术后并发症少，且对肾功能影响小，有利于病人术后快速康复。 |
| 英文摘要: |
| Objective To evaluate the clinical efficacy of Shuotong Jing in the treatment of upper urinary calculi and its effect on renal function.Methods Eighty patients with unilateral upper urinary tract calculi admitted to the urology department from Janu?ary 2018 to April 2019 were enrolled and randomly assigned into 2 groups(n＝40):Shuotong Jing group(S Group)and ureteros? copy group(group C).The operation time，stone clearance rate，complication rate(infection，fever，hematuria，ureteral mucosal inju? ry)of two groups of patients，α1 microglobulin in urine and serum levels of cystatin C before and after surgerywerecompared.Re? sults The operation time in group C was(59±10)min，the stone removal rate was 82.5%，and the complication rate was 20%， while the operation time in group S was(36±9)min，the stone removal rate was 97.5%，and complications occurred.The rate was 2.5%；the levels of α1 microglobulin in group C and group S at 12h after surgery were(9.33±1.03)mg/L and(5.06±1.02)mg/L， respectively，and at 24h after surgery were(13.05±1.09)) mg/L and(7.19±0.96)mg/L，respectively；serum cystatin C in group C and group S at 12h after surgery was(1.33±0.38)mg/L and(0.92±0.31)mg/L，respectively，and at 24h after surgerywas(1.62±0.66)mg/L and(1.26±0.40)mg/L，respectively，the above indicators were statistically different between the two groups(P＜0.05). Conclusion The treatment of upper urinary calculi，Shuotong Jing lithotripsy requires short operation time，high stone clearance rate，less postoperative complications，and little effect on renal function，which is conducive to rapid recovery after surgery. |
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