| 刘玉龙,舒冰.螺内酯致单侧男性乳腺增生 1例并文献复习[J].安徽医药,2022,26(4):845-848. |
| 螺内酯致单侧男性乳腺增生 1例并文献复习 |
| Spironolactone-induced unilateral gynecomastia: a case report and literature review |
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| DOI：10.3969/j.issn.1009-6469.2022.04.047 |
| 中文关键词: 螺内酯 药物相关性副作用和不良反应 男子乳腺发育 病例报告 |
| 英文关键词: Spironolactone Drug-related side effects and adverse reactions Gynecomastia Case report |
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| 中文摘要: |
| 目的分析螺内酯对单侧男性乳腺增生( gynecomastia，GYN)的影响。方法对 1例 80岁心力衰竭病人口服螺内酯引起的单侧 GYN进行病例分析并文献复习。结果病人经过近 8个月口服螺内酯治疗后，左侧乳房疼痛、肿胀，考虑是螺内酯引起的 GYN。停药 1个月后，左侧乳房疼痛消退，肿胀缩小。结论老年病人长期服用螺内酯片仍引起的 GYN以双侧居多，当临床医生遇到单侧症状时，应考虑药物诱发病因的可能性。 |
| 英文摘要: |
| Objective To analyze the effect of spironolactone on unilateral gynecomastia (GYN).Methods one case analysis and literature review of unilateral GYN caused by oral spironolactone in an 80-year-old patient with heart failure was reported.Results Af ter 8 months of treatment, the left breast was found to be swollen and painful, which was suspected to be spironolactone-induced GYN. Within one month of stopping the medication, the pain in the left breast subsided followed by decrease in size of swelling.Conclu sions It is necessary to closely monitor the adverse reactions of elderly patients taking spironolactone tablets for a long time. Litera ture search indicate that GYN caused by spironolactone is mostly bilateral. When clinicians encounter unilateral presentation, theyshould consider the possibility of drug-induced etiology. |
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