| 李琪,曹阳,王琳,等.不同临床结局 Brugada综合征 2例的麻醉探讨[J].安徽医药,2024,28(4):782-785. |
| 不同临床结局 Brugada综合征 2例的麻醉探讨 |
| Anesthesia exploration in 2 cases of Brugada syndrome with different clinical outcomes |
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| DOI：10.3969/j.issn.1009-6469.2024.04.031 |
| 中文关键词: Brugada综合征 心律失常 除颤器，植入型 麻醉 围手术期 |
| 英文关键词: Brugada syndrome Arrhythmia Defibrillators, implantable Anesthesia Perioperative period |
| 基金项目:广州市科技计划项目( 202103000022) |
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| 中文摘要: |
| 目的探讨 2例不同临床结局 Brugada综合征的围术期麻醉要点。方法对 2015年 7月至 2016年 7月、 2022年 3—5月广州市红十字会医院收集到的 2例不同临床结局 Brugada综合征的麻醉病例进行分析总结。结果 1例 72岁的 Brugada病人，有多次晕厥病史，于 2013年植入心律转复除颤器(ICD)植入 ICD后晕厥症状消失，其后，“下肢静脉曲张”与“腹股沟疝气”在全身麻醉下行手术治疗， 2次围手术期均未出现恶性心律失常，不良事件。而另 1例 Brugada病人，则因是因“躯干、下肢烧伤”在全身麻醉下进行了清创植皮术，但在手术之前，并没有植入 ICD。与前 1例病人不同，该病人在 2次围手术期均发生了恶性心律失常事件， |
| 英文摘要: |
| Objective To explore the key points of perioperative anesthesia in 2 cases with different clinical outcomes of Brugada syndrome.Methods Two anesthesia cases with different clinical outcomes of Brugada syndrome in Guangzhou Red Cross Hospitalfrom July 2015 to July 2016 and March to May 2022 were analyzed and summarized.Results A 72-year-old Brugada patient with ahistory of multiple syncope was implanted with a cardioverter defibrillator (ICD) in 2013, and the syncope symptoms disappeared afterthe implantation of the ICD, during which varicose veins of the lower limbs and inguinal hernia were treated under general anesthesia.No adverse events of malignant arrhythmia occurred during the perioperative period. The other Brugada patient underwent debridementand skin grafting under general anesthesia for "burns to the trunk and lower extremities" without implantation of an implantable cardio?verter-defibrillator (ICD) before surgery. Unlike the previous patient, this patient experienced malignant arrhythmic events during bothperioperative periods and died within 1 year of follow-up.Conclusion Many perioperative pharmacologic and nonpharmacologic fac?tors may predispose to the occurrence of malignant arrhythmic events in patients with Brugada syndrome, whereas preoperative implan?tation of a pacemaker may reduce this risk, and an ICD is an important safeguard for perioperative safety. |
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