文章摘要
胡萨萨,董亚琳.临床药师对某院2015~2017年抗肿瘤辅助用药的干预对比研究[J].安徽医药,待发表.
临床药师对某院2015~2017年抗肿瘤辅助用药的干预对比研究
投稿时间:2019-07-31  录用日期:2019-08-16
DOI:
中文关键词: 抗肿瘤辅助用药  临床药师干预  评价  合理用药
英文关键词: 
基金项目:陕西省重点研发计划项目(编号:2019SF-197)
作者单位E-mail
胡萨萨 西安交通大学第一附属医院药学部 howtofly_00@163.com 
董亚琳 西安交通大学第一附属医院药学部 dongyalin@medmail.com.cn 
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中文摘要:
      目的 评价临床药师干预对合理使用抗肿瘤辅助用药的促进效果,为抗肿瘤辅助用药的合理应用提供参考。方法 比较2015~2017年干预组与对照组辅助用药使用金额排名前5的辅助用药使用率、辅助用药费用占比、用药频度(DDDs)、限定日费用(DDC)及药品利用指数(DUI),分析临床药师干预对抗肿瘤辅助用药的合理性促进作用。结果 2015~2017年两组的辅助用药使用率及辅助用药费用占比均呈下降趋势;干预组在2015年及2016年的人均辅助药费等指标均明显低于对照组(P<0.05),2017年也呈现降低趋势(P>0.05)。干预组的多烯磷脂酰胆碱DUI较高,核糖核酸Ⅱ的DDC及使用率较高;对照组的康莱特及核糖核酸Ⅱ的DDC及使用率偏高。结论 临床药师持续地干预能明显降低患者的经济负担,并能有效促进抗肿瘤辅助用药的合理使用。
英文摘要:
      Objective To evaluate the effect of clinical pharmacists" intervention on the rational use of anti-tumor adjuvant drugs, and to provide reference for their rational application. Methods Compare the use rates, sales amount ratios, defined daily dose system (DDDs), defined daily cost (DDC) and drug utilization index (DUI) of the top 5 adjuvant drugs between the intervention group and the control group from 2015 to 2017, and analyze the rationality of clinical pharmacists" intervention on the rational use of anti-tumor adjuvant drugs. Results From 2015 to 2017, the use rate and the sales amount ratios of anti-tumor adjuvant drugs in the two groups showed a downward trend. In the intervention group, the per capita adjuvant drug fee and the other indicators in 2015 and 2016 were significantly lower than the control group (P<0.05), and the trend was also reduced in 2017 (P>0.05). The DUI of polyene phosphatidylcholine in the intervention group was higher, and the DDC and use rate of ribonucleic acid Ⅱwere higher; The DDC and use rate of kanglaite and ribonucleic acid Ⅱ in the control group were higher. Conclusion Continuous intervention by clinical pharmacists can significantly reduce the economic burden of patients and can effectively promote the rational use of anti-tumor adjuvant drugs.
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