| 荆睿,何斌.疼痛敏感性与骨质疏松性椎体骨折微创术后疗效的临床研究[J].安徽医药,2025,29(10):2084-2089. |
| 疼痛敏感性与骨质疏松性椎体骨折微创术后疗效的临床研究 |
| A clinical study of pain sensitivity and efficacy after minimally invasive surgery in patients with osteoporotic vertebral compression fracture |
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| DOI：10.3969/j.issn.1009-6469.2025.10.035 |
| 中文关键词: 疼痛测定 敏感性 疼痛敏感性问卷 骨质疏松性骨折 经皮椎体成形术 |
| 英文关键词: Pain measurement Sensitivity Pain sensitivity questionnaire Osteoporotic fractures Percutaneous vertebroplasty |
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| 中文摘要: |
| 目的研究疼痛敏感性对骨质疏松性椎体压缩性骨折( OVCF)病人行 PVP术后疼痛变化及功能恢复情况的影响，并探讨疼痛敏感性评估为病人制定个性化诊疗方案的意义。方法选取 2022年 7月至 2022年 12月重庆市璧山区人民医院及重庆市璧山区中医院收治的 77例 OVCF病人作为研究对象，根据疼痛敏感性问卷( PSQ)评分分为高敏感组(高疼痛敏感性组， n= 22，PSQ≥6.0分)和低敏感组(低疼痛敏感性组， n=55，PSQ<6.0分)。病人均接受 PVP手术治疗，比较两组病人术前及术后的视觉模拟评分(VAS)、日本骨科协会评分( JOA)、 Oswestry功能障碍指数评分( ODI)、健康调查简表( SF-36)分析 PSQ评分与病人的疼痛及功能障碍评分有无相关性。结果高敏组末次随访时 SF-36评分为 433.33(390.33，461.16)分，低，敏组末次随访时 SF-36评分为 480.83(447.33，521.66)分，差异有统计学意义( P<0.001)。且两组术前及随访 1个月、 3个月、 6个月的 VAS、JOA、ODI评分均差异有统计学意义( P<0.05)。高敏感组病人 VAS和 ODI评分高于低敏感组， JOA和 SF-36评分低于低敏感组。 PSQ评分与术前及术后的 VAS、JOA、ODI评分之间存在显著相关关系， PSQ评分与 VAS和 ODI评分之间为显著正相关，与 JOA评分之间为显著负相关。结论疼痛敏感性越高，病人术前、术后疼痛及功能障碍越明显，术后生活质量相对较差。术前对病人进行疼痛敏感性的评估有助于预测病人手术疗效，对于制定个体化治疗方案具有一定参考价值。 |
| 英文摘要: |
| Objective To study the effect of pain sensitivity on the changes of pain and functional recovery in osteoporotic vertebralcompression fracture (OVCF) patients after percutaneous vertebroplasty(PVP), and to explore the significance of pain sensitivity assess-ment for making personalized diagnosis and treatment plan for patients.Methods 77 patients with OVCF admitted to Chongqing Bis-han People's Hospital and Chongqing Bishan Hospital of Traditional Chinese Medicine from July 2022 to December 2022 were selectedas the research subjects. According to pain sensitivity questionnaire (PSQ) score, the patients were divided into high sensitivity group(high pain sensitivity group, n=22, PSQ≥6.0) and low sensitivity group (low pain sensitivity group, n=55, PSQ < 6.0). All patients weretreated with PVP surgery. Preoperative and postoperative visual analogue scale (VAS), Japanese orthopaedic association (JOA) score, os-westry functional disability Index (ODI), and SF-36 scores were compared between the two groups, and the correlation between PSQscores and pain and dysfunction scores was analyzed, with P<0.05 being statistically significant.Results At the final follow-up of the high sensitivity group, the SF-36 score was 433.33 (390.33, 461.16)points, while at the final follow-up of the low sensitivity group, the SF-36 score was 480.83 (447.33, 521.66)points. The difference was statistically significant (P<0.001).There were significant differences in VAS, JOA and ODI scores before surgery and at 1, 3 and 6 months of follow-up. VAS and ODI scores in high sensitivity group were higher than those in low sensitivity group. JOA and SF-36 scores were lower than those of low sensitivity group. There was a significantcorrelation between PSQ score and VAS, JOA and ODI scores measured during preoperative and postoperative follow-up (P < 0.05), PSQscore was significantly positively correlated with VAS and ODI scores, and significantly negatively correlated with JOA scores.Conclu. sions The higher the pain sensitivity, the more obvious the pain and dysfunction before and after surgery, and the worse the quality oflife after surgery. The evaluation of patients' pain sensitivity before operation is helpful to predict the operative effect of patients, and hascertain reference value for formulating individual treatment plan. |
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