| 舒冰,张圣雨,王崇薇,等.某三甲医院心内科572例药品不良反应报告分析[J].安徽医药,2018,22(1):170-174. |
| 某三甲医院心内科572例药品不良反应报告分析 |
| Adverse drug reaction reports in department of cardiology of a 3A hospital:an analysis of 572 cases |
| 投稿时间：2017-02-21 |
| DOI： |
| 中文关键词: 药品不良反应 心内科 报告 分析 |
| 英文关键词: ADR department of cardiology report analysis |
| 基金项目: |
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| 中文摘要: |
| 目的 研究某院心内科药品不良反应(ADR)发生的规律、特点,探讨ADR发生的可能原因及影响因素,以期为临床安全、合理用药提供参考。方法 对该院2012—2015年上报的心内科ADR报告进行统计分析。结果 572例心内科药品不良反应报告中,男性306例(53.50%),女性266例(46.50%)；70~＜80岁人群ADR发生率最高,有188例(32.87%)；ADR发生率最高的给药途径为静脉滴注206例(36.01％),其次是口服给药205例(35.84%)；新的ADR报告113例(19.76%),严重的ADR报告28例(4.90%)；心血管药物所致的不良反应最多,有410例(71.68%),其次为中药注射剂73例(12.76%)；以消化系统损害145例(25.35%)最为常见。结论 心血管药物(抗血小板、抗凝和调脂药物)、中药注射剂是心内科ADR监测重点药物类别,60岁以上患者是ADR监测重点人群,静脉滴注是ADR监测重点给药途径,消化系统损害是提示ADR发生的重要信号。 |
| 英文摘要: |
| Objective To study the characteristics and regularities of adverse drug reactions (ADR) reported in Department of Cardiology,The Provincial Hospital Affiliated to Anhui Medical University,and to explore the possible causes and influencing factors of the ADR,so as to provide reference for using drugs safely and rationally in clinic. Methods ADRs reported in Department of Cardiology from 2012 to 2015 were analyzed statistically. Results Among 572 cases of ADR reported,306 cases were males(53.50%) and 266 cases were females (46.50%).188 cases of patients aged 70-＜80 held the highest proportion of 32.87%.The highest rate of administration route leading to ADRs was intravenous drip (206 cases,36.01%),followed by oral administration(205 cases,35.84%).There were 113 cases (19.76%)of new ADR and 28 cases (4.90%) of serious ADR.The most frequent ADRs resulted from cardiovascular drugs (410 cases,71.68%),followed by traditional Chinese medicine injections (73 cases,12.76%).Among ADRs involving organs and/or systems,digestive system was most commonly damaged (145 cases,25.35%). Conclusions Medical staff must strengthen monitoring on ADRs of cardiovascular drugs including antiplatelet,anticoagulant and lipid-lowering drugs and traditional Chinese medicine injections,ADRs via intravenous drip and ADRs in patients aged 60 and over.Damages to digestive system is the important signal suggesting occurrence of ADRs. |
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