文章摘要
李海霞,后世翔,祝子明.综合干预对骨科Ⅰ类切口围手术期预防使用抗菌药物效果分析[J].安徽医药,2019,23(5):1040-1043.
综合干预对骨科Ⅰ类切口围手术期预防使用抗菌药物效果分析
Efficacy of comprehensive intervention on the prophylactic use of antibiotics in the orthopedic I-type incision operation
  
DOI:10.3969/j.issn.1009-6469.2019.05.055
中文关键词: 抗生素预防  外科伤口感染  住院时间  费用,药物  抗菌药  医院,骨科
英文关键词: Antibiotic prophylaxis  Surgical wound infection  Length of stay  Fees,pharmaceutical  Anti-bacterial agents  Hospitals,osteopathic
基金项目:
作者单位E-mail
李海霞 宣城市人民医院药学部,安徽 宣城 241000  
后世翔 宣城市人民医院药学部,安徽 宣城 241000  
祝子明 宣城市人民医院药学部,安徽 宣城 241000 ziming2006@163.com 
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中文摘要:
      目的 探讨综合干预对骨科I类切口围手术期预防使用抗菌药物的影响。方法 抽取宣城市人民医院2017年1—12月Ⅰ类切口手术病例599份,与2016年数据进行对比,并对干预后预防性抗菌药物合理性进行评价分析,对比干预效果。结果 2017年抗菌药物预防应用合理性明显改善,抗菌药物预防使用率由59.46%下降至46.24%,差异有统计学意义(χ2=22.216,P<0.001)。预防用人均抗菌药物费用由对照组的189.16元下降为79.53元,住院总药费由对照组的2 496.62元下降为1 605.39元(P<0.001)。药物品种选择及术后用药时间的不合理给药频次较去年同期明显减少(P<0.01)。结论 综合干预使该院骨科Ⅰ类切口手术预防性使用抗菌药物情况明显好转,对促进临床安全、有效、经济地应用抗菌药物起到积极作用。
英文摘要:
      Objective To evaluate the effects of comprehensive intervention on perioperative antimicrobial prophylaxis in the orthopedic Itype incision operation.Methods 599 I-type incision operation cases were extracted in Xuancheng People’s Hospital from January to December 2017.In order to examine effects of intervention,the rationality of preventive anti-bacterial drugs was evaluated after intervention and compared with that of 2016.Results In 2017,rationality of anti-bacterial preventive medication was improved and its utilization rate was significantly reduced from 59.46% to 46.24% (χ2=22.216,P<0.001).The cost of per capita antiseptic drugs decreased from 189.16 yuan to 79.53 yuan,and the cost of total inpatient drugs decreased from 2 496.62 yuan to 1 605.39 yuan (P<0.001).Utilization frequency of irrational drugs also obviously decreased in drugs selection and drugs use timing of post of operation (P<0.01).Conclusion The status of anti-bacterial preventive medication of I-type incision operation in a certain hospital has gained favorable results through comprehensive intervention,and it has positive role on stimulating clinical anti-bacterial medication,which was safer,more effective and more economical.
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