| 康凌汝,简小兵.基于数据挖掘对中药治疗糖尿病合并骨质疏松的规律分析[J].安徽医药,2020,24(3):572-575. |
| 基于数据挖掘对中药治疗糖尿病合并骨质疏松的规律分析 |
| Data mining?based analysis of traditional Chinese medicine in treating diabetes mellitus combined with osteoporosis |
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| DOI：10.3969/j.issn.1009?6469.2020.03.038 |
| 中文关键词: 糖尿病/中药疗法 骨质疏松 /中药疗法 补阳 活血祛瘀 补气药 数据挖掘 聚类分析 关联规则 |
| 英文关键词: Diabetes mellitus/drug therapy(TCD) Osteoporosis/drug therapy(TCD) Reinforcing yang Blood?activating and blood?stasis removing Qi?reinforcing drugs Data mining Cluster analysis Association rule |
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| 中文摘要: |
| 目的利用数据挖掘研究分析治疗糖尿病合并骨质疏松的中药使用规律。方法通过检索数据库包括中国知网数据库(2007年 2月至 2019年 7月)、万方数据知识服务平台( 2009年 1月至 2019年 7月)、维普中文科技期刊数据库( 2006年 1月至 2019年 7月)近 10年关于糖尿病合并骨质疏松的文献建立数据库。采用数据挖掘技术，分析高频率的中药以及药物之间关联。结果通过纳入标准及排除标准筛选出中医药治疗糖尿病合并骨质疏松文献 146篇，共纳入 54个处方 95种中药。其中频数高的中药为牛膝、当归、淫羊藿、山药、黄芪、山萸肉、枸杞子、丹参、骨碎补、补骨脂、熟地，中药种类以助阳药、活血祛瘀药、补气药、养血药、祛风湿药为主，经聚类分析后得出 4类高频率中药，关联规则分析出两种中药相关的有 6条， 3种中药相关的有 26条。结论糖尿病合并骨质疏松中医治疗上使用助阳药的频数最多，其次是活血化瘀药及补气药；药物之间配伍的原则多以温补肾阳为治法，兼以滋阴、养血、补气等治疗。 |
| 英文摘要: |
| Objective To explore the usage rule of traditional Chinese medicine in treating diabetes mellitus combined with osteo?porosis based on data mining.Methods The database was established by searching CNKI(from Feb.2007 to July 2019)，Wanfangdatabase(from Jan.2009 to July 2019)，VIP database(from Jan.2006 to July 2019)for literatures on diabetes complicated with os?teoporosis in recent 10 years.The data mining was used to analyze the association between high frequency Chinese medicines anddrugs.Results Through inclusion criteria and exclusion criteria，146 literatures on the treatment of diabetes combined with osteo? porosis by traditional Chinese medicine were screened out，involving 54 recipes and 95 herbs.The high frequency herbs were Radix Achyranthis Bidentatae，Angelicae Sinensis Radix，Epimedii Folium，Dioscoreae Rhizoma，Astmgali Radix，Corni Fructus，Lycii Fruc? tus，Salviae Miltiorrhizae，Drynariae Rhizoma，Psoraleae Fructus，Rehmanniae Radix Praeparata.The main drug categories were yang? strengthening drugs，blood?activating and blood?stasis removing drugs，qi invigorating drugs，blood?nourishing drugs and wind?damp?dispelling.Four categories of high frequency Chinese medicines were identified by cluster analysis.Association rule analysis resultsin 6 association rules for drug pairs and 26 association rules for the compatibility of 3 drugs.Conclusions In traditional Chinese medicine treatment of diabetic osteoporosis，yang?strengthening drugs are the most frequently used，followed by blood?activating andblood?stasis removing drugs and qi invigorating drugs.The principle of compatibility of drugs is to warm and tonify the kidney?uang， and to nourish Yin，blood and tonify Qi. |
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