| 付豹,王进峰,刘晓飞,等.万应膏外敷联合手术治疗浆细胞性乳腺炎 30例疗效观察[J].安徽医药,2021,25(1):64-67. |
| 万应膏外敷联合手术治疗浆细胞性乳腺炎 30例疗效观察 |
| Observation on clinical efficacy of 30 cases of Wanying ointment combined with surgery in treatment of plasma cell mastitis |
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| DOI：10.3969/j.issn.1009?6469.2021.01.016. |
| 中文关键词: 乳腺炎 浆细胞 软膏 中草药 引流术 外敷 万应膏 炎性因子 复发 |
| 英文关键词: Mastitis Plasma cells Ointments Drugs,Chinese herbal Drainage External application Wanying ointment Inflammatory factor Recurrence |
| 基金项目:河北省中医药管理局科研计划项目(2019449) |
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| 中文摘要: |
| 目的观察万应膏外敷联合手术治疗浆细胞性乳腺炎(PCM)的临床疗效。方法选取石家庄市中医院 2017年 5月至 2018年 3月诊治的 60例 PCM病人并按照随机数字表法划分成对照组和治疗组，每组各 30例。对照组单一应用手术治疗，治疗组采取万应膏外敷联合手术治疗。对比两组临床疗效、中医症状体征积分、血常规、炎性因子水平及复发情况。其中临床疗效与复发情况用 %表示，组间比较以 χ2检验；中医症状体征积分、血常规、炎性因子水平用 xˉ± s表示，以 t检验，当 P＜0.05时，表示差异有统计学意义。结果治疗后，治疗组总有效率 93.33%较对照组 70.00%优(P＜0.05)；两组中医各症状体征积分、细胞(WBC)计数及C ?反应蛋白(CRP)、白细胞介素 ?6(IL?6)、肿瘤坏死因子 α(TNF?α)水平［(7.22±1.39)、(6.52±1.05)×109/L，白 |
| 英文摘要: |
| Objective To observe the clinical effect of Wanying Ointment combined with surgery in the treatment of plasma cell mastitis(PCM).Methods 60 PCM patients treated in Shijiazhuang Hospital of Traditional Chinese Medicine from May 2017 toMarch 2018 were selected and divided into control group and treatment group according to random number table method，30 cases in each group.The control group was treated with surgery alone，while the treatment group was treated with Wanying ointment com? bined with surgery.The clinical efficacy，TCM symptom and sign score，blood routine，inflammatory factor level and recurrence of the two groups were compared.The clinical efficacy and recurrence were expressed by‘%’and the comparison between groups was tested.The scores of symptoms and signs，blood routine and inflammatory factors in TCM were expressed by(xˉ± s)and t test，when P＜0.05，the difference was statistically significant.Results After treatment，the total effective rate of the treatment group was 93.33%，better than that of the control group 70%(P＜0.05).The score of symptoms and signs，white blood cell(WBC)C?reactive protein(CRP)，interleukin 6(IL?6)，tumor necrosis factor?α(TNF?α)in the two groups［(7.22±1.39)×109/L(6.52±1.05109/L，)，(5.46±2.30)mg/L(3.18±1.93)mg/L，(34.62±2.85)ng/L(26.24±2.29)ng/L，(50.21±4.54)ng/L(41.19±3.50)ng/L］were im? proved compared with those before treatment［(8.13±1.74)×109/L(8.07±1.58)×109/L，(8.84±3.26)mg/L(8.71±3.02)mg/L，(44.25±3.39)ng/L(43.61±3.14)ng/L，(72.51±6.47)ng/L(71.68±5.49)ng/L］(P＜0.05)，and the improvement in the treatment group was better than that in the control group(P＜0.05).The recurrence rate of the treatment group was 3.33%，which was lower than 20.00% of the control group(P＜0.05).Conclusion Wanying ointment combined with surgery for PCM patients has better clinical effect than surgery alone，it can significantly reduce TCM symptoms and signs，effectively improve blood routine and inflam? matory factor levels，and greatly reduce the recurrence rate of the disease. |
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