| 覃国勇,张颖.前庭自旋转试验与血浆同型半胱氨酸水平检测对耳源性眩晕疾病的诊断价值[J].安徽医药,2018,22(5):885-888. |
| 前庭自旋转试验与血浆同型半胱氨酸水平检测对耳源性眩晕疾病的诊断价值 |
| The diagnostic value of vestibular self-rotation test and plasma homocysteine in the diagnosis of otogenic vertigo |
| 投稿时间：2017-01-16 |
| DOI： |
| 中文关键词: 耳源性眩晕疾病 同型半胱氨酸血症 前庭自旋转试验 诊断价值 |
| 英文关键词: otogenic vertigo homocysteinemia vestibular rotation test diagnostic value |
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| 中文摘要: |
| 目的 探讨血浆同型半胱氨酸水平检测与前庭自旋转试验对耳源性眩晕病的诊断价值。 方法 纳入确诊为耳源性眩晕疾病患者80例,其中梅尼埃病26例、良性阵发性位置性眩晕34例、前庭神经炎20例,另设健康对照组80例。分别于确诊后检查各组的前庭自旋转试验、血浆同型半胱氨酸水平,分析前庭自旋转试验中水平增益、相移,垂直增益、相移,水平非对称性的异常与耳源性眩晕疾病的相关性,同型半胱氨酸水平与耳源性眩晕疾病的相关性。 结果 三组耳源性眩晕疾病患者的同型半胱氨酸水平[(19.64±5.34)、17.43±4.53)、16.76±4.36) μmol·L-1]均明显高于健康对照组(10.78±5.43) μmol·L-1,差异有统计学意义(P＜0.05)；三组同型半胱氨酸血症的发病率61.54%、50.00%、40.00%均明显高于健康对照组5.00%,差异有统计学意义(P＜0.05)；前庭自旋转试验结果异常48例,非对称性异常8例,均与前庭损伤侧相符合,异常结果中垂直增益异常6例,且均为增益降低；水平增益升高2例、增益降低30例,相位异常40例,水平增益及垂直增益均异常5例,均表现为相位延迟,垂直相位异常6例,水平相位异常26例。 结论 前庭自旋转试验与血浆同型半胱氨酸水平检测是定位诊断的一种客观检测手段,是耳源性眩晕疾病中敏感筛查方法,也可为前庭功能检查及指导治疗提供依据。 |
| 英文摘要: |
| Objective To evaluate the diagnostic value of vestibular self-rotation test and plasma homocysteine in patients with otogenic vertigo. Methods Eighty patients with otogenic vertigo were included,including 26 cases of Meniere′s disease,34 cases of benign paroxysmal positional vertigo and 20 cases of vestibular neuritis.The vestibular self-rotation test and plasma homocysteine level were examined after the diagnosis.The correlation between the levels of horizontal gain,phase shift,vertical gain,phase shift,horizontal asymmetry abnormality and otogenic vertigo disease,and the correlation between homocysteine and ear vertigo were analyzed. Results The homocysteine levels in patients with otogenic vertigo of the three groups [(19.64±5.34),(17.43±4.53),(16.76±4.36) μmol·L-1,respectively] were significantly higher than the control group (10.78±5.43) μmol·L-1,the difference was statistically significant (P<0.05).The incidences of homocysteine in the three groups were 61.54%,50.00% and 40.00%,which were significantly higher than 5.00% in the control group,the difference was statistically significant (P<0.05).There were 48 cases of abnormal vestibular self-rotation test results,8 cases of asymmetry abnormalities,which were consistent with the vestibular injury side,and 6 cases of abnormal vertical gain,which were all gain reduction.There were 2 cases of horizontal gain increase,30 cases of horizontal gain reduction,40 cases of phase abnormality.The horizontal gain and vertical gain were abnormal in 5 cases,all of which showed phase delay.There were 6 cases of vertical phase abnormality and 26 cases of horizontal phase abnormality. Conclusions Vestibular self-rotation test and plasma homocysteine are an objective method for the diagnosis of otogenic vertigo,and may be useful for the test of vestibular function and the diagnosis of disease. |
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