| 周咏,张斌华.安徽省某三甲医院医护人员的甲状腺结节检出情况及其影响因素分析[J].安徽医药,2022,26(8):1576-1579. |
| 安徽省某三甲医院医护人员的甲状腺结节检出情况及其影响因素分析 |
| Detection of thyroid nodules among medical staff in a tertiary hospital of Anhui Province and its influencing factors |
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| DOI：10.3969/j.issn.1009-6469.2022.08.021 |
| 中文关键词: 甲状腺结节 影响因素 医护人员 |
| 英文关键词: Thyroid nodules Influencing factors Medical staff |
| 基金项目:中国健康促进基金(CHP-2022-HSP)；安徽省高校人文社会科学(SK2017A0199) |
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| 中文摘要: |
| 目的调查安徽某三甲医院医护人员的甲状腺结节患病情况，并对其影响因素进行分析。方法收集2020年皖南医学院弋矶山医院医护人员健康体检数据，包含一般情况(性别、年龄、身高体质量、收缩压、舒张压)、血常规、血脂四项、肝功能十项、肾功能四项、尿常规、癌胚抗原(CEA)、甲胎蛋白(AFP)、糖类抗原199(CA199)、糖类抗原125(CA125)以及甲状腺B超结果等，分析甲状腺结节的检出率，分析甲状腺结节发生的影响因素。结果甲状腺结节检出600例，检出率为51.37%(男性甲状腺结节有157例，检出率为43.73%；女性甲状腺结节有443例，女性检出率为54.82%)。在甲状腺结节组内高血压178例，糖尿病57例，分别占40.18%和9.5%，与非甲状腺结节组相比差异有统计学意义(P<0.05)。甲状腺结节组与非甲状腺结节组在年龄［(52.41±18.25)岁比(40.10 ±14.54)岁］和收缩压上比较，差异有统计学意义(P<0.05)。甲状腺结节组与非甲状腺结节组在嗜酸性细胞百分比［1.80(1.20，2.68)%比1.90(1.20，3.00)%］、红细胞(RBC)、血红蛋白(HGB)、红细胞压积(HCT)、平均红细胞体积(MCV)、平均血红蛋白量(MCH)、血小板(PLT)、血小板比积(PCT)、空腹血糖(GLU)、总胆固醇(TC)、高密度脂蛋白(HDL)、胱抑素C、尿素氮(Bun)、糖化血红蛋白a［(5.94 ±0.73)%比(5.70 ±0.45)%］、糖化血红蛋白c［(1.42 ±0.85)%比(1.31 ±0.80)%］、CEA上比较，差异有统计学意义(P<0.05)。采用多因素logistic回归分析，结果显示年龄、糖尿病、嗜酸性细胞百分比是甲状腺结节发生的独立影响因素。结论医护人员甲状腺结节发生率较一般人群的发生率高，且年龄、糖尿病是甲状腺结节发生的危险因素，嗜酸性细胞百分比是甲状腺结节发生的保护因素。 |
| 英文摘要: |
| Objective To investigate the prevalence of thyroid nodules among medical staff in a tertiary hospital of Anhui Province and to analyze its influencing factors.Methods The health examination data of the medical staff in Yijishan Hospital of Wannan Medi?cal College in 2020 was collected, including general conditions (gender, age, height and body mass, systolic blood pressure, diastolic blood pressure), blood routine examination, blood lipids examination, liver function test, renal function test, urine routine test, carcino?embryonic antigen (CEA), alpha-fetoprotein (AFP), carbohydrate antigen 199 (CA199), carbohydrate antigen 125 (CA125) and thyroid B-ultrasound results, etc. The detection rate of thyroid nodules was analyzed, and the influencing factors of the occurrence of thyroid nodules were analyzed.Results Six hundred cases of thyroid nodules were detected with a detection rate of 51.37%, including 157(43.73%) cases of male thyroid nodules and 443 (54.82%) cases of female thyroid nodules. There were 178 (40.18%) cases of hyperten?sion and 57 (9.5%) cases of diabetes in the thyroid nodule group, and the difference was statistically significant compared with the nonthyroid nodule group (P<0.05). There were significant differences in age[(52.41±18.25)year vs. (40.10 ±14.54)year] and systolic blood pressure between the thyroid nodule group and the non-thyroid nodule group (P<0.05). Statistically significant differences were seen in the percentage of eosinophils[1.80(1.20,2.68)% vs. 1.90(1.20,3.00)%], red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT),mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), platelets (PLT), platelet crit (PCT), fasting blood glucose (GLU), total cholesterol (TC), high density lipoprotein (HDL), cystatin C, blood urea nitrogen (Bun), glycated hemoglobin a[(5.94 ±0.73)% vs. (5.70 ±0.45)%], glycated hemoglobin c[(1.42 ±0.85)% vs. (1.31 ±0.80)%], and carcinoembryonic antigen (CEA) between thy?roid nodule group and non-thyroid nodule group (P<0.05). Multivariate logistic regression analysis results showed that age, diabetes and eosinophil percentage were independent influencing factors for the occurrence of thyroid nodules.Conclusion The incidence of thyroid nodules among medical staff is higher than that of the general population, and age and diabetes are risk factors for the occur?rence of thyroid nodules, while the percentage of eosinophils is a protective factor. |
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