| 陈瑞文,戚睿.胆道 125I粒子条支架治疗恶性梗阻性黄疸的临床研究[J].安徽医药,2022,26(11):2236-2239. |
| 胆道 125I粒子条支架治疗恶性梗阻性黄疸的临床研究 |
| Clinical study of biliary 125I seed strips stent in treating malignant obstructive jaundice |
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| DOI：10.3969/j.issn.1009-6469.2022.11.026 |
| 中文关键词: 黄疸，阻塞性 125I粒子条支架 普通金属支架 |
| 英文关键词: Jaundice,obstructive 125I seed strips stent Common metal stent |
| 基金项目:淮南市科技计划项目( 2018A3613) |
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| 中文摘要: |
| 目的研究使用胆道 125I粒子条支架和普通金属支架治疗恶性梗阻性黄疸( MOJ)的疗效差异。方法回顾性分析 2016年 1月至 2019年 12月在淮南市第一人民医院介入放射科治疗的 30例恶性梗阻性黄疸病人的临床资料，其中粒子组为使用 125I粒子条支架治疗的 15例，普通组为使用普通金属支架治疗 15例。根据肝功能及胆道肿瘤标记物等指标评价近期疗效，生存时间评价远期疗效。结果粒子组及普通组均可显著降低肝功能指标，粒子组同时可显著降低胆道肿瘤标记物指标。此外，粒子组中位生存时间及平均生存时间［( 207.00±41.22)d，(210.19±35.74)d］均长于普通组［( 90.00±41.12)d，(81.77±17.93) |
| 英文摘要: |
| Objective To investigate the difference in the efficacy of biliary 125I seed strips stent and common metal stent in treating malignant obstructive jaundice (MOJ).Methods The clinical data of 30 malignant obstructive jaundice patients treated in the Depart.ment of Interventional Radiology, Huainan First People's Hospital from January 2016 to December 2019 were retrospectively analyzed.Among them, the particle group was 15 cases treated with 125I seed strips stent, the common group was treated with common metal stent in 15 cases. The short-term curative effect, survival time and long-term curative effect were evaluated according to liver function and biliary tumor markers.Results The indices of liver function were significantly decreased in both the particle group and the commongroup. Meanwhile, the biliary tumor marker in the particle group was significantly reduced. Additionally, the median survival time andthe mean survival time in the particle group were (207.00±41.22) days and (210.19±35.74) days respectively, both of which were longerthan those in the common group [(90.00±41.12) days and (81.77±17.93) days] respectively, the difference between the two groups werestatistically significant (P<0.05).Conclusion The treatment of malignant obstructive jaundice by biliary 125I seed strips stent can sig. nificantly improve the survival time of patients. |
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