| 夏阳阳,张苗.腹膜透析钙磷代谢紊乱患者使用低钙腹膜透析液及碳酸镧的随访分析[J].安徽医药,2016,20(7):. |
| 腹膜透析钙磷代谢紊乱患者使用低钙腹膜透析液及碳酸镧的随访分析 |
| Follow up of low calcium dialysate and lanthanum carbonate in peritoneal dialysis patients with calcium and phosphorus metabolism disorder |
| 投稿时间：2016-03-28 录用日期：2016-06-01 |
| DOI：同意录用 |
| 中文关键词: 腹膜透析 高钙 甲状旁腺激素 低钙腹膜透析液 碳酸镧 |
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| 中文摘要: |
| 调查我科腹膜透析患者血钙(Ca)、血磷(P)及甲状旁腺激素的情况,并观察通过使用低钙腹膜透析液结合药物的治疗高Ca、高P及甲旁亢的效果。方法：统计2010年以后在南京鼓楼医院规律随访一直使用普通钙腹膜透析液(钙离子浓度为1.75mmol/L)一年以上时间的腹膜透析患者血Ca、血P及全段甲状旁腺激素(iPTH)水平。根据患者血Ca、血P及iPTH水平挑选120例高Ca、高P、甲旁亢患者,平均分为A、B两组,A组改用低钙腹膜透析液(钙离子浓度为1.25mmol/L),B组改用低钙腹膜透析液的同时加用碳酸镧降磷治疗。结果：六个月后,A组与之前比较,血Ca降低,血P、iPTH升高(P<0.05),B组与之前比较血Ca、血P、iPTH降低(P<0.05),半年后B组与A组比较血Ca、血P、iPTH降低(P<0.05)。结论：对于出现高Ca、高P及高iPTH的患者建议使用低钙腹膜透析液,同时必须加强使用碳酸镧降磷治疗。 |
| 英文摘要: |
| objective: To investigate blood calcium,phosphate and PTH in peritoneal dialysis patients of our department.To observe the treatment effect of high blood calcium,phosphate and PTH by use low calcium dialysate with medicine.Methods: We investigated blood calcium,phosphate and intact parathyroid hormone (iPTH) in peritoneal dialysis patients who were regularly followed up at last one year using regular calcium dialysate (calcium concentration was 1.75mmol/L) in Drum Tower Hospital of Nanjing after 2010.We selected 120 cases of patients with high calcium, phosphorus and iPTH and the average is divided into A, B two groups.Group A changed to low calcium dialysate (calcium concentration was 1.25mmol/L) .Group B changed to low calcium dialysate and lanthanum carbonate. Result:After six months,Group A compared with before, blood calcium decreased, phosphorus and iPTH increased(P<0.05).Group B compared with before,blood calcium, phosphorus and iPTH decreased(P<0.05).Also after six month Group B compared with Group A,blood calcium, phosphorus and iPTH decreased(P<0.05).Conclusion:We recommend to use low calcium dialysate in high blood calcium,,phosphate and PTH ,meanwhile we must enhance treating high blood phosphorus using lanthanum carbonate. |
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