| 吴琪,陈肖东,苏峰,等.微片的特点和研究进展[J].安徽医药,2016,20(1):5-8. |
| 微片的特点和研究进展 |
| Characterization and research progress of mini-tablets |
| 投稿时间：2015-09-17 |
| DOI： |
| 中文关键词: 多单元型制剂 微片 |
| 英文关键词: multiple unit dosage form mini-tablets |
| 基金项目:十二五国家"重大新药创制"科技重大专项项目(No 2012ZX09401006)作者简介:吴琪,女,硕士研究生 |
|
| 摘要点击次数: 3273 |
| 全文下载次数: 132 |
| 中文摘要: |
| 在口服缓控释给药系统中,与单元型制剂相比,多单元型制剂的药物高度分散在胃肠道内,可以减少药物突释、提高用药安全性,还可以准确控制剂量、提高患者顺应性。多单元型给药系统包括颗粒、微球、微丸和微片等。该文主要介绍微片的特点和近年来的一些研究进展。 |
| 英文摘要: |
| In oral sustained and controlled release drug delivery systems, compared with the single unit dosage form, multiple unit dosage form drug,highly dispersed in the gastrointestinal tract, can reduce drug burst release and increase the bioavailability, accurately control the dose, and also improve the compliance of patients. The multiple unit dosage form includes particles, microspheres, pellets, and mini-tablets. This article mainly introduces the characteristics of the mini-tablets and some research progress in recent years. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
