| 马俊鹏,王新玲,李芸,等.维吾尔药铁力木不同极性部位体外抗氧化作用的研究[J].安徽医药,2016,20(3):421-424. |
| 维吾尔药铁力木不同极性部位体外抗氧化作用的研究 |
| Antioxidant activities of different polarity chemical constituents from Mesua ferrea in vitro |
| 投稿时间：2015-10-19 |
| DOI： |
| 中文关键词: 铁力木 抗氧化活性 铁离子还原反应 DPPH自由基 超氧自由基 |
| 英文关键词: Mesua ferrea antioxidant activity ferric reducing antioxidant power DPPH· O·-2 |
| 基金项目:国家“十二五”科技支撑计划(No 2012BAI30B02) |
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| 摘要点击次数: 3542 |
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| 中文摘要: |
| 目的 研究维吾尔药铁力木不同极性部位的体外抗氧化活性。方法 以Vc为对照,通过测定铁力木乙醇提取物、水提取物及乙醇提取物石油醚(沸程60~90℃)、乙酸乙酯、正丁醇、水各萃取物对Fe3+的还原能力、对DPPH自由基(DPPH·)和超氧自由基(O·-2)的清除能力,研究铁力木的体外抗氧化活性。结果 铁力木各部位对Fe3+均表现出一定的还原能力,对DPPH·及O·-2均表现出一定的清除作用,但作用均弱于VC。其中水层及正丁醇层对Fe3+的还原能力较强,而其石油醚层和乙酸乙酯层还原能力较弱；水层和水提取物对DPPH·具有一定的清除能力；石油醚层及水提取物清除O·-2的作用较强。结论 铁力木具有较好的抗氧化能力。 |
| 英文摘要: |
| Objective To study the antioxidant activity of the different polarity chemical constituents from the buds of Mesua ferrea. Methods The capacity of ferric reducing antioxidant power and scavenging DPPH·,O·-2 of the ethanol total extract,water extract,petroleum ether fraction,ethylacetate fraction,n-butanol fraction and water fraction from the buds of Mesua ferrea were evaluated by Fe3+ reduction capacity experiments and DPPH·,O·-2 scavenging assay in vitro at different concentrations.The results were compared with those of positive control vitamin C (VC).Results The ferric reducing antioxidant power and DPPH·,O·-2 scavenging activity of different polarity chemical constituents from the buds of Mesua ferrea were weaker than those of VC. Among them,the water fraction and n-butanol fraction exhibited strong reduction power of Fe3+. The water extract and water fraction demonstrated strong scavenging activities of DPPH·. The petroleum ether fraction and water extract demonstrated the strong scavenging activities of O·-2. ConclusionsMesua ferrea has a strong antioxidant activity. |
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