王晶,东星,吴鸿雁,等.多种方法联合干预预防妊娠期高血压疾病的临床分析[J].安徽医药,2016,20(5):917-920. |
多种方法联合干预预防妊娠期高血压疾病的临床分析 |
Clinical analysis of multiple methods combined to prevent hypertensive disorder complicating pregnancyWANG Jing1,DONG Xing2,WU Hong-yan2,et al (1.Department of Obstetrics and Gynecology,Beijing 100700,China;2.Department of General Surgery,General Hospital of Beijing Military Command,Beijing 100700,China) Abstract:Objective |
投稿时间:2015-12-03 |
DOI: |
中文关键词: 高血压,妊娠性 营养政策 膳食,减重 妊娠结局 |
英文关键词: Hypertension,Pregnancy-Induced Nutrition Policy Diet,Reducing Pregnancy Outcome |
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中文摘要: |
目的 探讨多种方法联合干预预防妊娠期高血压疾病的效果,为该病的预防提供新的可行性方法。 方法 选取孕妇共1 050例,分为3 组。A组380例孕妇采用饮食管理,同时进行补锌、钙、叶酸、维生素B12等药物干预,B组350例孕妇进行适度锻炼、体质量管理等干预,C组320例孕妇进行常规孕产期宣教和产检,比较3组血清锌、钙、叶酸、维生素B12水平及妊娠合并症、并发症的发病率。结果(1)A组孕妇的血钙、锌、叶酸、维生素B12水平均高于B组及C组(P<0.01),B组孕妇的血钙、锌水平高于C组(P<0.01)。(2) 妊娠期高血压疾病、HELLP综合征、羊水过少的发生率A组及B组均明显低于C组,差异有统计学意义 (均P<0.01);A组低于B组,但差异无统计学意义(P>0.05)。(3) A组孕妇的剖宫产、产后出血、早产、新生儿窒息发生率均明显低于C组 (P<0.01) ;B组孕妇的剖宫产、产后出血发生率均明显低于C 组 (P<0.01)。结论 孕期注重饮食调节,并进行补充钙、锌、叶酸、维生素B12及适度锻炼、体质量管理等联合干预,可以有效的降低妊娠期高血压疾病的发生率,改善妊娠结局。 |
英文摘要: |
Objective To investigate the effect of combined treatment of various methods to prevent hypertensive disorder complicating pregnancy(HDCP),and to provide a new feasible method for the prevention of this disease.Methods Totally 1 050 cases of pregnant outpatients recorded in General Hospital of Beijing Military Command from January to December 2014 were randomized into 3 groups.Group Awith 380 pregnant women underwent diet management,and were supplied with zinc,calcium,folic acid,vitamin B12.Group Bwith 350 pregnant women were given exercise regulation and weight management.Group Cwith 320 pregnant women had routine prenatal examination.The serum levels of zinc,calcium,folic acid,vitamin B12 and the incidence of pregnancy complications were compared among 3 groups.Results The calcium,zinc,folic acid and vitamin B12 levels in group Awere significantly higher than those in group Band C(P<0.01),and the calcium and zinc levels of group Bwere higher than those of group C(P<0.01).The incidences of HDCP,HELLP syndrome and oligohydramnios in group Aand Bwere significantly lower than those in group C(P<0.01).The incidences of cesarean section,postpartum hemorrhage,premature delivery,neonatal asphyxia were significantly lower in group Athan those in group C (P<0.01);The incidences of cesarean section,postpartum hemorrhage in group Bwere significantly lower than those in group C (P<0.01).Conclusions Diet regulation combined with the intervention of calcium,zinc,folic acid,vitamin B12 and body weight management can effectively reduce the incidence of HDCP and improve pregnancy outcome. |
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