| 王重.盐酸氨溴索辅助治疗早产儿呼吸衰竭的临床观察[J].安徽医药,2016,20(8):1581-1583. |
| 盐酸氨溴索辅助治疗早产儿呼吸衰竭的临床观察 |
| A clinical observation of Ambroxol Hydrochloride in the adjuvant treatment of premature infants with respiratory failure |
| 投稿时间：2016-04-08 |
| DOI： |
| 中文关键词: 呼吸功能不全 氨溴索 婴儿,早产 治疗结果 |
| 英文关键词: Respiratory insufficiency Ambroxol Lnfant,premature Treatment outcome |
| 基金项目: |
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| 中文摘要: |
| 目的 观察盐酸氨溴索辅助治疗早产儿呼吸衰竭的临床疗效。方法 共纳入早产呼吸衰竭患儿64例,采用简单随机化分组中的随机数字表法分为治疗组34例和对照组30例。治疗组给予常规治疗的同时,静脉滴注盐酸氨溴索辅助治疗；对照组未给予盐酸氨溴索辅助治疗,其余治疗方法与治疗组相同。观察两组的临床疗效。结果 与对照组相比,治疗组患儿血气分析值包括动脉血氧分压PaO2(72.1±7.5) mmHg、动脉血二氧化碳分压PaCO2(45.5±6.8) mmHg及动脉血氧饱和度SaO2(87.3±6.1)%均明显改善(P<0.05)、辅助通气时间缩短为(53.60±16.2) h、相关并发症发生率降低至5.88%、平均住院时间缩短至(13.53±3.15) d、住院费用降低至(5 799.00±668.00) 元,患儿转归率提升至85.29%。结论 盐酸氨溴索辅助治疗早产儿呼吸衰竭的临床疗效显著。 |
| 英文摘要: |
| Objective To observe the clinical efficacy of ambroxol hydrochloride in the adjuvant treatment of premature infants with respiratory failure.Methods Totally 64 premature infants with respiratory failure were included and assigned into treatment group (n=34) and control group (n=30) by simple randomized grouping method.The control group was treated with routine treatment,while the treatment group was given intravenous injection of ambroxol hydrochloride based on the routine treatment.The clinical efficacy was compared between the two groups.Results Compared with the control group,the curative effect was significantly improved in the treatment group(P<0.05).For the treatment group,the PaO2 was (72.1±7.5) mmHg,PaCO2 was (45.5±6.8) mmHg and SaO2was (87.3±6.1)%,the assisted ventilation time reduced to (53.60±16.2) h,the incidence of related complications reduced to 5.88%,the average hospitalization time reduced to (13.53±3.15) d.,hospitalization expense reduced to (5 799.00±668.00) Yuan.The curative rate was up to 85.29%.Conclusions The clinical efficacy of ambroxol hydrochloride in the adjuvant treatment of premature infants patients with respiratory failure is obvious. |
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