文章摘要
万金华,朱艳琼.复方短效口服避孕药、左炔诺孕酮宫内缓释系统和安全套在剖宫产瘢痕妊娠清宫术后的避孕效果比较[J].安徽医药,2016,20(10):1949-1952.
复方短效口服避孕药、左炔诺孕酮宫内缓释系统和安全套在剖宫产瘢痕妊娠清宫术后的避孕效果比较
A comparative contraceptive effect among compound short-acting oral contraceptives,levonorgestrel releasing intrauterine system and condoms after cesarean scar pregnancy curettage
投稿时间:2016-07-19  
DOI:
中文关键词: 剖宫产瘢痕妊娠清宫术  复方短效避孕药  左炔诺孕酮宫内缓释系统  安全套  避孕
英文关键词: Cesarean scar pregnancy curettage  Compound short-acting contraceptives  Levonorgestrel releasing intrauterine system  Condom  Contraception
基金项目:湖北省科技成果项目(EK2013D170078001619)复方短效口服避孕药、左炔诺孕酮宫内缓释系统和安全套在剖宫产瘢痕妊娠清宫术后的避孕效果比较万金华1,朱艳琼2 (1.荆门市康复医院妇科,湖北 荆门 448000;2.荆门市第二人民医院妇产科,湖北 荆门 448000)复方短效口服避孕药、左炔诺孕酮宫内缓释系统及安全套在剖宫产瘢痕妊娠清宫术后的避孕效果研究 万金华,朱艳琼
作者单位
万金华 荆门市康复医院妇科,湖北 荆门 448000 
朱艳琼 荆门市第二人民医院妇产科,湖北 荆门 448000 
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中文摘要:
      目的 研究复方短效口服避孕药、左炔诺孕酮宫内缓释系统及安全套在剖宫产瘢痕妊娠清宫术后的避孕效果及安全性。方法 选择112例行子宫动脉栓塞联合清宫术治疗的剖宫产瘢痕妊娠患者,根据术后避孕措施分为三组,即避孕药组39例;口服复方短效避孕药组37例,即患者于清宫术后立即放置左炔诺孕酮宫内缓释系统(曼月乐);安全套组36例,患者在术后采用安全套进行避孕。对三组患者进行随访,比较三组患者B超检查结果、意外妊娠情况和月经量改变情况。结果 随访1年,避孕药组患者避孕总有效率为94.88%,曼月乐组患者避孕总有效率为100.00%;安全套组避孕总有效率为86.11%,但三组避孕效果比较,尚不能认为三组间避孕总有效率差异有统计学意义。随访1年,避孕药组和安全套组各有1例再发剖宫产瘢痕妊娠(CSP),曼月乐组无再发病例。B超复查三组患者均未出现切口破裂或者损伤。三组患者均未见月经量增加病例,根据卡方分割法进一步比较三组月经改变情况,曼月乐组患者术后患者术后3、6、12个月月经量减少比例均显著高于安全套组和避孕药组(P<0.017),避孕药组术后3个月时的月经量减少比例显著高于安全套组(P<0.017)。三组患者均未发生严重不良反应,无性生活不适主诉。结论 子宫动脉栓塞联合清宫术后CSP患者可采取复方短效口服避孕药和宫内放置曼月乐避孕,可使患者获益更多,安全可靠。
英文摘要:
      Objective To explore the contraceptive efficacy and safety of compound short-acting oral contraceptives,levonorgestrel releasing intrauterine system and condoms after cesarean scar pregnancy curettage.Methods Totally 112 CSP patients,who were treated uterine artery embolization combined with curettage,were randomized into 3 groups.Patients (39 cases) in the contraceptive pill group were treated with compound short-acting contraceptives,patients (37 cases) in mirena group were placed Mirena (levonorgestrel-releasing intrauterine system) after curettage immediately,and patients (36 cases) in condom group were given condoms contraception.Three groups of patients were followed up to compare ultrasonic examination results,unexpected pregnancy and menstrual flow change.Results Patients were followed up for 1 year.The total effective rates of patients in contraceptive pill group,Mirena patient group and condoms contraception group were 94.88%,100.00% and 86.11%,respectively.There wasn’t significant difference in total contraceptive effective rate among the three groups.There was 1 case of recurrent CSP in contraceptive pills group and condoms group respectively,but there was no recurrence in Mirena group.Ultrasonic examination showed there were noincision rupture or damage,no increase in the amount of menstruation in the 3 groups.With chi-square division method,the menstrual changes of the three groups were compared.The decrease of menstruation in the patients of Mirena group was significantly higher than those of the condom group and the contraceptive pill group (P<0.017) at 3,6 and 12 months postoperatively.The menstrual blood loss decreased significantly in contraceptive pill group at 3 months after curettage compared with the other two groups (P<0.017).There were no serious adverse events and complaints about asexual life in the 3 groups.Conclusions After uterine artery embolization combined with uterine curettage CSP patients can take marvelon and Mirena intrauterine contraception,which is safe,reliable,and can benefit patients more.
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