| 汪艳,陈乐.肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的预后影响[J].安徽医药,2016,20(11):2163-2165. |
| 肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的预后影响 |
| Prognostic impact of transcatheter arterial chemoembolization in the treatment of hepatitis Bassociated hepatocellular carcinoma |
| 投稿时间：2016-04-12 |
| DOI： |
| 中文关键词: 乙型肝炎相关性肝癌 肝动脉化疗栓塞治疗 危险因素 |
| 英文关键词: Hepatitis Brelated hepatocellular carcinoma Transcatheter arterial chemoembolization Risk factor |
| 基金项目: |
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| 摘要点击次数: 2805 |
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| 中文摘要: |
| 目的 探讨肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的预后影响因素。方法 对行肝动脉化疗栓塞治疗的150例患者临床资料进行回顾性分析,观察肝动脉化疗栓塞治疗3年后患者生存率,并对肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的预后影响因素采用单因素分析及Logistic多因素分析。 结果 (1)150例乙型肝炎相关性肝癌患者经肝动脉化疗栓塞治疗3年后,存活64例,死亡86例, 3年生存率为42.67%,死亡率为57.33%。(2)单因素分析得出:假包膜形成、癌灶数目多、门脉癌栓、肿瘤直径大、胸腔转移、腹腔转移均为肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的危险因素为肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的保护因素,均差异有统计学意义(P＜0.05)。(3)经Logistic多因素回归分析得出:假包膜形成、癌灶多发、门脉癌栓、肿瘤直径≥5 cm、胸腔转移、腹腔转移均为肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的危险因素。结论 假包膜形成、癌灶多发、门脉癌栓、肿瘤直径≥5 cm、胸腔转移、腹腔转移均为肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的危险因素。 |
| 英文摘要: |
| Objective To investigate the prognostic factors of hepatic artery chemoembolization in the treatment of hepatitis Bassociated hepatocellular carcinoma.Methods Clinical data of 150 cases undergoing hepatic artery chemotherapy embolization were retrospectively analyzed.Three-year survival rate of the patients was observed,and prognostic influence factors were analyzed using single factor analysis and Logistic multivariate regression analysis.Results Three years after the treatment,of 150 cases of HBV related hepatocellular carcinoma patients,64(42.67%)cases survived,and 86(57.33%)cases died.The single factor analysis showed that pseudocapsule formation,tumor number,tumor thrombus in the portal vein,diameter of tumor,pleural and peritoneal metastases were risk factors of hepatic artery chemoembolization in the treatment of hepatitis Bvirus associated hepatocellular carcinoma.The differences were statistically significant(P<0.05).The Logistic multivariate regression analysis showed that pseudocapsule formation,cancer lesions,portal vein tumor thrombus,tumor diameter greater than 5 cm,pleural and peritoneal metastases were risk factors of hepatic arterial chemoembolization in the treatment of hepatitis Bvirus associated hepatocellular carcinoma.Conclusions Formation of pseudocapsule,multiple tumor,portal vein tumor thrombus,tumor diameter greater than or equal to 5 cm,pleural metastasis,and peritoneal metastasis are risk factors of transcatheter arterial chemoembolization in the treatment of hepatitis Bvirus related hepatocellular carcinoma(HCC). |
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