| 戎佩佩.医院癌痛病人超说明书用药分析[J].安徽医药,2017,21(1):163-165. |
| 医院癌痛病人超说明书用药分析 |
| Analysis of off-label drug use in cancer pain in a hospital |
| 投稿时间：2016-08-03 |
| DOI： |
| 中文关键词: 癌痛 超说明书用药 |
| 英文关键词: Cancer pain Off-label drug use |
| 基金项目: |
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| 摘要点击次数: 3306 |
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| 中文摘要: |
| 目的 分析医院癌痛病人超说明书用药的合理性,为临床合理用药提供依据,并进一步规范医院超说明书用药行为。方法 随机抽取2016年上半年300份癌痛病人的住院病历,通过查阅药品说明书、临床诊疗指南、文献等对其中超说明书用药的合理性进行分析评价。结果 医院癌痛病人超说明书用药共计59例,用药类型包括超适应证用药、超适应人群用药、超给药途径用药、超给药间隔用药等,部分有国内外指南推荐,有高证据级别文献支持或理论依据支持。结论 医院癌痛病人超说明书用药现象较为普遍,且基本合理,医院应进一步规范超说明书用药行为,以提高临床合理用药水平。 |
| 英文摘要: |
| Objective To analyze the rationality of off-label drug use in cancer pain patient to provide scientific basis for clinical rational drug use and further regulate the off-label drug use in our hospital. Methods A random sample of 300 hospital records of cancer pain selected from our hospital were analyzed and evaluated by searching drug instruction,cancer pain guidelines and literatures. Results The off-label drug use in cancer pain in our hospital includes off-label indication,off-label administration,off-label population and so on.Most of them were recommended by domestic and overseas guidelines,or based on high-level evidence or pharmacologic theory. Conclusion The off-label drug use in cancer pain in our hospital is common and basically rational.Our hospital need to further standardize the management of off-label use in order to improve the level of rational use of drugs. |
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