| 刘勇.鼻内镜手术结合玉屏风颗粒治疗慢性鼻窦炎伴鼻息肉的疗效及对免疫功能的影响[J].安徽医药,2017,21(2):339-342. |
| 鼻内镜手术结合玉屏风颗粒治疗慢性鼻窦炎伴鼻息肉的疗效及对免疫功能的影响 |
| Effect of nasal endoscopesurgery combined with Yupingfeng particle in treating chronic rhinosinusitis with nasal polyps and the influence on immune function |
| 投稿时间：2016-05-17 |
| DOI： |
| 中文关键词: 鼻内镜手术 慢性鼻窦炎伴鼻息肉 玉屏风颗粒 免疫功能 |
| 英文关键词: Nasal endoscopesurgery Chronic rhinosinusitis with nasal polyps Yupingfeng particle Immune function |
| 基金项目: |
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| 摘要点击次数: 2736 |
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| 中文摘要: |
| 目的 探讨鼻内镜手术后辅助玉屏风颗粒对慢性鼻窦炎伴鼻息肉的疗效以及对免疫功能的影响。 方法 70例慢性鼻窦炎伴鼻息肉病人按随机数字表法随机分为对照组(35例)和观察组(35例)。对照组采取鼻内镜手术治疗。观察组在对照组基础上给予玉屏风颗粒,一次5 g,1 d 3次,连续4周。比较两组视觉模拟评分法(VAS)症状积分、鼻内镜Lund-Kennedy评分、鼻窦Lund-Mackay评分、并发症和复发率。检测两组细胞免疫功能水平。 结果 术后3个月,观察组病人VAS各指标评分显著少于对照组(P＜0.01)。术后1个月,观察组病人的鼻内镜Lund-Kennedy和鼻窦CT Lund-Mackay评分显著少于对照组(P＜0.01)。3个月随访观察组的并发症发生率和复发率分别为8.57％和2.86％,明显低于对照组的31.43％和22.86％(P＜0.05)。术后3个月,观察组病人的CD3+和CD4+显著多于对照组,CD8+少于对照组,差异有统计学意义(P＜0.01)。 结论 鼻内镜手术联合玉屏风颗粒治疗慢性鼻窦炎伴鼻息肉的疗效明显,还有利于提高病人的细胞免疫功能。 |
| 英文摘要: |
| Objective To investigate efficacy of nasal endoscopesurgery plus Yupingfeng particle in Treating chronic rhinosinusitis with nasal polyps and the influence on immune function. Methods 70 patients of chronic rhinosinusitis with nasal polyps were randomly divided into control group(35 cases) and observation group(35 cases) referring to the random number table method.Patients of control group was treated by nasal endoscopesurgery.Additionally cases of observation group were treated with Yupingfeng particle, 5 g per time, tid, and for 4 weeks.Scores of VAS symptoms, nasal endoscopy Lund-Kennedy, paranasal sinus CT Lund-Mackay, complication, and recurrence rate were compared between two groups.Immune function was detected in both groups. Results 3 months after operation, index scores of VAS were lower than that of control group(P＜0.01).Scores of Nasal endoscopy Lund-Kennedy and paranasal sinus CT Lund-Mackay of observation group were evidently lower than control group 1 month after operation(P＜0.01).By 3 months follow up, complication and recurrence rate were 8.57% and 2.86% respectively, which were lower than control group as 31.43% and 22.86%(P＜0.05).3 months after operation, CD3+ and CD4+ in observation group were obviously more, while CD8+ was lower, than control group with statistic difference(P＜0.01). Conclusion Efficacy of nasal endoscopesurgery plus Yupingfeng particle in treating chronic rhinosinusitis with nasal polyps is definite, and which can especially promotes immune function. |
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