| 吴玲玲,夏燕,封扬,等.恶性中胚叶混合瘤6例临床病理学特征[J].安徽医药,2017,21(7):1234-1236. |
| 恶性中胚叶混合瘤6例临床病理学特征 |
| Malignant mullerian mixed tumor:a clinicopathological features of 6 cases |
| 投稿时间：2016-08-08 |
| DOI： |
| 中文关键词: 恶性中胚叶混合瘤 卵巢 子宫 子宫颈 病理学特征 |
| 英文关键词: Malignant mullerian mixed tumor Ovary Uterus cervix Pathological features |
| 基金项目: |
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| 摘要点击次数: 2510 |
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| 中文摘要: |
| 目的 探讨卵巢、子宫体及子宫颈恶性中胚叶混合瘤(MMMT)的临床病理学特征。 方法 收集6例MMMT的临床资料、影像学表现,回顾性分析其临床病理学特征。 结果 MMMT的组织学癌为中-低分化浆液性腺癌、高-中分化子宫内膜样腺癌、低分化鳞状细胞癌及未分化癌；肉瘤同源性为纤维肉瘤、低级别子宫内膜间质肉瘤、平滑肌肉瘤及未分化高级别多形性肉瘤,异源性为软骨肉瘤。免疫组化:癌表达细胞角蛋白(CK)；肉瘤表达波形蛋白(Vim)、肌动蛋白(SMA)、结蛋白(Desmin)、肌动蛋白结合蛋白(Calponin)、S-100蛋白、CD10、CD68、CD99。 结论 MMMT属于高度侵袭性肿瘤,诊断主要依据组织学形态并结合免疫组化染色。 |
| 英文摘要: |
| Objective To investigate the clinicopathological features of malignant mullerian mixed tumor (MMMT) in ovary,uterus,cervix. Methods The clinicopathological and imaging features of 6 cases diagnosed MMMT were retrospectively analyzed. Results MMMT epithelial components appeared in the poorly differentiated serous adenocarcinoma,high-differentiation in endometrioid adenocarcinoma,poorly-differentiated squamous cell carcinoma,undifferentiated carcinoma.Mesenchymal components appeared in fibrosarcoma,low grade endometrial stromal sarcoma,leiomyosarcoma,undifferentiated high-level pleomorphic sarcoma and heterology chondrosarcoma.Immunohistochemistry showed that CK expression in epithelium,and Vim,SMA,Desmin,Calponin,S-100,CD10,CD68,CD99 expression in sarcoma. Conclusions MMMT as a highly invasive tumor was diagnosed,according to immunohistochemistry combination with the pathological imaging characteristics. |
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