| 孟现奇,赵娜,左靖,等.某院儿童和孕产妇药品不良反应情况分析[J].安徽医药,2017,21(10):1938-1942. |
| 某院儿童和孕产妇药品不良反应情况分析 |
| Analysis ofadverse drug reactionsinreports of children and maternal in ahospital |
| 投稿时间：2017-01-20 |
| DOI： |
| 中文关键词: 药品不良反应 儿童 孕产妇 |
| 英文关键词: ADR Children Maternal |
| 基金项目: |
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| 摘要点击次数: 3777 |
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| 中文摘要: |
| 目的 统计分析2016年该院儿童和孕产妇用药后产生药品不良反应(ADR)的规律、特点,为该类特殊人群临床合理用药提供参考依据。方法 收集该院2016年上报的98例儿童ADR报告,利用Excel软件进行回顾性统计分析；对该院2016年上报的3例孕产妇ADR报告进行病例讨论。结果 98例儿童ADR报告中一般不良反应96例(占97.96%),新的一般的不良反应2例(2.04%),无严重不良反应/事件发生；患儿最小年龄为1 d,最大13岁,婴幼儿期(≤3岁)患儿65例(66.33%),占比最大；98例ADR均为静脉给药所致；共涉及24个品种,其中抗菌药物14个；以皮肤及附件损害(74例,75.51%)和消化系统损害(21例,21.43%)最为常见。3例孕产妇ADR报告中有1例严重ADR报告。结论 儿童和孕产妇生理结构特殊,应规范用药,加强用药监护,并做好该类特殊人群的ADR上报工作,以促进临床合理用药。 |
| 英文摘要: |
| Objective To analyze characteristicsof the adverse drug reactions (ADRs) in children and maternal in Suzhou Municipal Hospital in 2016 and provide references forrational use of medicines.Methods The 98 cases of ADRs in children in the year of 2016 were collected and summarized by Excel.The 3 cases of ADRs in maternalwere discussed respectively.Results 98 cases of ADRs reportsin children were classified into general category (96 cases,97.96%) and new general category(2 cases,2.04%).No severeADRs were reported.The age of children ranged from 1 day old to 13 years old.The infants and young children period (3 years old or less) in children with 65 cases (66.33%) were accounted for the largest.All of the 98 cases of ADRs were caused by intravenous drug delivery and 24 kinds of drugs including 14 kinds of antimicrobial drugs were involved.The skin and accessories (74 cases,75.51%) and the digestive system(21 cases,21.43%) were damaged the most common.Among the 3 cases of ADRs inmaternal,there was 1 case of severe ADR.Conclusion With special physiological structure,children and maternal should be treated with programmed drugs administration and the supervision on drugs administration should be strengthened.Otherwise,the ADR reporting work of these special populations should be optimized to promote rational drug use in the clinic. |
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