王羊洋,高大胜.心脏型脂肪酸结合蛋白在急性心肌梗死诊断中的应用进展[J].安徽医药,2017,21(11):1968-1970. |
心脏型脂肪酸结合蛋白在急性心肌梗死诊断中的应用进展 |
The progress in applications of heart-type fatty acid binding protein in the diagnosis of acute myocardial infarction |
投稿时间:2016-11-10 |
DOI: |
中文关键词: 心脏型脂肪酸结合蛋白 急性心肌梗死 诊断 |
英文关键词: Heart-fatty acid binding protein Acute myocardial infarction Diagnosis |
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中文摘要: |
该文综述了心脏型脂肪酸结合蛋白在急性心肌梗死早期临床诊断中的应用进展,详细介绍了心脏型脂肪酸结合蛋白的生物学特性,并从它对急性心肌梗死的诊断效能、危险分层、预后评价、指导治疗和判断疗效等各个方面所起的作用作了着重的论述。分析表明在急性心肌梗死的早期诊断中,心脏型脂肪酸结合蛋白相对于其他心肌损伤标志物,如心肌肌钙蛋白、肌酸激酶同工酶和肌红蛋白,其具有较高的灵敏性和特异性,且在判定严重程度、疗效判断、预后评估等方面均有一定的临床价值,是急性心肌梗死可靠的生化指标。 |
英文摘要: |
This paper reviews the application and progress of heart-type fatty acid binding protein in the early diagnosis of acute myocardial infarction,and introduces its biological characteristics detailed.The diagnostic efficiency,risk stratification,prognosis evaluation,guiding clinical treatment and curative effect judgment of heart-type fatty acid binding protein in acute myocardial infarction are discussed emphatically.The analysis showed that heart-type fatty acid binding protein,compared with other myocardial injury markers,including cardiac troponin I,creatine kinade isoenzyme-myocardial band,myoglobin,has a higher sensitivity and specificity in the early diagnosis of acute myocardial infarction.Above all,heart-type fatty acid binding protein has a certain clinical value in determining the severity,efficacy judgment,prognosis assessment,and it is a reliable biochemical index of the acute myocardial infarction. |
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