| 王莉.盐酸米诺环素软膏和热牙胶根管充填治疗重度牙周-牙髓联合病变48例[J].安徽医药,2018,22(6):1159-1162. |
| 盐酸米诺环素软膏和热牙胶根管充填治疗重度牙周-牙髓联合病变48例 |
| Minocycline hydrochloride ointment and hot tooth root canal filling in treating 48 patients with severe periodontal-pulp combined diseases |
| 投稿时间：2017-08-30 |
| DOI： |
| 中文关键词: 牙周疾病 牙髓疾病 根管充填 根管充填材料 米诺环素 |
| 英文关键词: Periodontal diseases Dental pulp diseases Root canal obturation Root canal filling materials Minocycline |
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| 中文摘要: |
| 目的 探讨盐酸米诺环素软膏及热牙胶根管充填联合治疗重度牙周-牙髓联合病变的临床效果。 方法 选取95例重度牙周-牙髓联合病变患者采用随机数字表法分为对照组与观察组。两组均行热牙胶根管充填治疗及牙周基础治疗,在此基础上对照组给予碘甘油注满牙周袋治疗,观察组给予盐酸米诺环素软膏注满牙周袋治疗。对比两组临床疗效、治疗前后牙周情况[探诊深度(probing depth,PD)、牙龈指数(gingival index,GI)、临床附着水平(clinical attachment level,CAL)]。治疗后随访3个月,对比两组生活质量(the short-form 36 item health survey questionnaire,SF-36)评分。 结果 观察组临床总有效率91.67%较对照组76.60%高(P＜0.05)；两组治疗前PD、GI、CAL比较差异无统计学意义(P＞0.05),治疗后两组PD、GI、CAL均有改善(P＜0.05),观察组PD(3.79±0.34)mm、GI(0.86±0.21)分、CAL(0.89±0.11)mm均优于对照组PD(4.87±0.47)mm、GI(1.19±0.33)分、CAL(1.13±0.24)mm,P＜0.001；两组治疗前SF-36评分比较差异无统计学意义(P＞0.05),治疗后3个月两组SF-36评分均有改善(P＜0.001),观察组(72.83±11.19)分高于对照组(67.42±8.24)分(P＜0.01)。 结论 盐酸米诺环素软膏及热牙胶根管充填治疗重度牙周-牙髓联合病变,疗效显著,可有效改善牙周组织情况,有利于提高患者生活质量。 |
| 英文摘要: |
| Objective To investigate the clinical effect of Minocycline Hydrochloride Ointment and hot gutta percharoot canal filling in the treatment of severe periodontal-pulpal joint disease. Methods Ninety-five patients with severe periodontal - pulpal joint disease were assigned into observation group and control group according to the random number table method.Two groups were treated with root canal filling with hot gum and basic periodontal treatment.On this basis,the control group was given iodine glycerol,and the observation group was given intravenous Minocycline Hydrochloride Ointment.The clinical efficacy and periodontal condition including probing depth (PD),gingival index (GI),clinical attachment level (CAL) before and after treatment of two groups were compared.After follow-up for 3 months,the short-form 36 item health survey questionnaire (SF-36) scores of the two groups were compared. Results The clinical curative effect of the observation group the total effective rate (91.67%) was higher than that of the control group (76.60%) (P<0.05).There were no significant differences in PD,GI and CAL between the two groups before treatment (P>0.05),after treatment,the levels of PD,GI and CAL were all improved (P<0.001);PD (3.79±0.34) mm,GI (0.86±0.21) points,CAL (0.89±0.11) mm of the observation group were superior to PD (4.87±0.47) mm,GI (1.19±0.33) points,CAL (1.13±0.24) mm of the control group (P<0.05).There was no significant difference in SF-36 scores between the two groups before treatment (P>0.05);the SF-36 scores were improved at 3 months after treatment (P<0.001),and the SF-36 scores of the observation group (72.83±11.19) points were higher than those of the control group (67.42±8.24) points (P<0.01). Conclusions Minicillin Hydrochloride Ointment and hot gutta-percha root canal filling in the treatment of severe periodontal-pulpal joint disease has a significant effect,which can effectively improve the periodontal tissue and is conducive to improving the quality of life of patients. |
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