齐丽.白细胞介素-17A与支气管哮喘的研究进展[J].安徽医药,2018,22(9):1651-1653. |
白细胞介素-17A与支气管哮喘的研究进展 |
Research advance of interleukin-17A and bronchial asthma |
投稿时间:2017-02-22 |
DOI: |
中文关键词: 哮喘 白细胞介素-17A 细胞因子 |
英文关键词: Asthma Interlerkin-17A Cytokine |
基金项目:合肥市2016年度科技攻关计划项目(合科〔2017〕3号) |
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中文摘要: |
支气管哮喘是由多种细胞和细胞组分参与的慢性气道炎症性疾病,以气道中多种炎症细胞浸润、黏液分泌增多、气道重塑及气道高反应性为特征。白细胞介素-17A(IL-17A)是近年来发现的一种由Th17等多种细胞产生的细胞因子。有研究表明IL-17A参与了哮喘的发病过程,该文就IL-17A与哮喘的关系加以综述。 |
英文摘要: |
Bronchial asthma is regarded as a common airway disorder that is characterized by chronic airway inflammation of various cytokines.It is characterized by inflammatory cell infiltration,increased mucus secretion,airway remodeling and airway hyperreactivity.Interleukin (IL)-17A is a cytokine released from Th17 and other cell types.The evidence suggests that IL-17A is involved in the pathogenesis of asthma,this review will summarize the relationship between IL-17A and asthma. |
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