| 廖晓现,成力,朱洪斌.血糖水平与慢性心力衰竭合并2型糖尿病患者预后的相关性[J].安徽医药,2018,22(10):1962-1964. |
| 血糖水平与慢性心力衰竭合并2型糖尿病患者预后的相关性 |
| Correlation between blood glucose level and prognosis in patients with chronic heart failure and type 2 diabetes mellitus |
| 投稿时间：2016-08-29 |
| DOI： |
| 中文关键词: 心力衰竭 糖尿病,2型 血糖 血红蛋白A,糖基化 预后 |
| 英文关键词: Heart failure Diabetes mellitus,type 2 Blood glucose Hemoglobin A,glycosylated Prognosis |
| 基金项目: |
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| 摘要点击次数: 1999 |
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| 中文摘要: |
| 目的 研究血糖水平与慢性心力衰竭合并2型糖尿病患者预后的相关性。 方法 选取2014年4月至2016年3月重庆市开州区人民医院收治的90例慢性心力衰竭合并2型糖尿病患者为研究对象,并将患者按照随访中测定的糖化血红蛋白(HbA1c)值划分为血糖达标组(HbA1c<7.0%)与血糖未达标组(HbA1c≥7.0%),对比两组患者联合主要心血管事件的发生率,并分析无联合主要心血管事件患者的生存率。 结果 与血糖达标组相比,血糖未达标组的空腹血糖及餐后2 h血糖水平差异有统计学意义,而且心力衰竭程度越重,糖化血红蛋白水平越高(P<0.05),联合主要心血管事件的发生率较高(3.77%比18.92%,P=0.018)；两组患者的N末端B型利钠肽原与左室射血分数水平差异无统计学意义(P=0.721,P=0.117)。 结论 将HbA1c控制在7.0%以下,可有效改善慢性心力衰竭合并2型糖尿病患者的预后水平。 |
| 英文摘要: |
| Objective To study the relationship between blood glucose level and prognosis in patients with chronic heart failure and type 2 diabetes mellitus.Methods Ninety patients with chronic heart failure complicated with type 2 diabetes in People's Hospital of Kaizhou District from April 2014 to March 2016 were selected as study subjects,and the determination of glycosylated hemoglobin (HbA1c) value during follow-up was used as criteria to assign patients into blood glucose standard group (HbA1c<7.0%) and blood glucose substandard group (HbA1c≥7.0%).The incidence of major cardiovascular events was compared between the two groups,and the survival rate of patients with no major cardiovascular events was analyzed. Results Compared with the blood glucose standard group,fasting blood glucose and 2-hour postprandial blood glucose levels in the blood glucose substandard group were increased significantly with the statistical significance;the more severe the heart failure,the higher the glycated hemoglobin level (P<0.05) and the incidence of major cardiovascular events (3.77% vs.18.92%,P=0.018).The differences of N-terminal pro-B-type natriuretic peptide and left ventricular ejection fraction level in the two groups were not statistically significant (P=0.721 and P=0.117,respectively). Conclusion Controlling HbA1C below 7% can effectively improve the prognosis of patients with chronic heart failure complicated with type 2 diabetes. |
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