| 谢爱香.新生儿感染性疾病主要致病菌及诱发感染的危险因素分析[J].安徽医药,2019,23(3):513-516. |
| 新生儿感染性疾病主要致病菌及诱发感染的危险因素分析 |
| Analysis of bacteria and risk factors of neonatal infectious diseases |
| 投稿时间：2017-08-11 |
| DOI： |
| 中文关键词: 新生儿感染 细菌 危险因素 |
| 英文关键词: Neonatal infection Bacteria Risk factor |
| 基金项目: |
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| 摘要点击次数: 1921 |
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| 中文摘要: |
| 目的 探讨新生儿感染性疾病细菌及其危险因素,为降低新生儿感染率提供参考依据。 方法 回顾性分析2016年1月至2016年12月濮阳市中医院小儿重症监护病房(NICU)收治的1 080例新生儿病人临床资料,对发生各系统感染的128例患儿,综合分析感染发生部位、疾病种类、细菌特征及危险因素。 结果 1 080例病人中各种感染128例,感染发生率11.85%；感染部位:呼吸系统感染60例(46.87%),血流感染38例(29.68%),皮肤、软组织损伤感染17例(13.28%),其它部位感染13例(10.16%)；新生儿感染主要致病菌为肺炎克雷伯菌28株(21.88%)、凝固酶阴性葡萄球菌29株(22.66%)、大肠埃希菌22株(17.19%)、B族链球菌(GBS)12株(9.38%)；在可能导致感染的因素中,新生儿性别和分娩方式之间差异无统计学意义(P＞0.05),胎龄、低体质量、住院时间、机械通气、侵入性操作、入住暖箱、羊水污染、胎膜早破、围产妇B族链球菌(GBS)筛查之间均差异有统计学意义(P＜0.05)。 结论 新生儿感染细菌广、危险因素多,合理选择抗菌药物,及时发现可能诱发感染的危险因素,并制定相应的防御措施,是降低新生儿感染性疾病发生率和多重耐药菌在新生儿病房传播的重要措施。 |
| 英文摘要: |
| Objective To investigate the bacteria of neonatal infection disease and its risk factors and to provide reference for clinical neonatal infection. Methods A retrospective study was conducted on the clinical data of 1 080 neonatal patients admitted to our hospital neonatal intensive care unit (NICU) from January 2016 to December 2016.Cases of 128 neonatal patients with systemic infections were analyzed comprehensively in the sites of infection,disease types,bacteria characteristics and risk factors. Results Among all the 1 080 patients,128 patients were infected thus the infectious rate was 11.85 %.Among the infectious cases,there were 60 cases of respiratory infection (46.87%),38 cases of bloodstream infection (29.68 %),17 cases of skin and soft tissue injury and infection (13.28%),and 13 cases of other sites of the infection (10.16%).The main pathogens of neonatal infection included 28 strains of Klebsiella pneumoniae (21.88%),29 strains of coagulase negative staphylococcus (22.66%),22 strains of Escherichia coli (17.19%),and 12 strains of Group B Streptococcus (GBS) (9.38%).Except for the gender and modes of delivery,other factors that might induce infections such as gestational age,low birth weight,hospitalization time,mechanical ventilation,invasive operation,incubator occupancy,amniotic fluid contamination,premature rupture of membranes and GBS screening for women in the period of late pregnancy were all statistically significant (P<0.05). Conclusions There are a wide range of neonatal infection pathogens and various risk factors.Rational selection of antibiotics,timely investigating of possible risk factors for infection,and developing corresponding preventive measures are important measures to reduce the number of neonates with infectious disease and to lower the risk of spreading multidrug-resistant bacteria in neonatal wards. |
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