| 赵利珍,卞京京,李燕敏,等.菊叶三七致肝小静脉闭塞病35例临床分析[J].安徽医药,2019,23(5):1057-1060. |
| 菊叶三七致肝小静脉闭塞病35例临床分析 |
| An analysis of 35 cases with gynura segetum-induced hepatic veno-occlusive disease |
| |
| DOI：10.3969/j.issn.1009-6469.2019.05.060 |
| 中文关键词: 肝静脉闭塞性疾病 景天三七 腹水 肝肿大 生物碱类 |
| 英文关键词: Hepatic veno-occlusive disease Sedum alzoon Ascites Hepatomegaly Alkaloids |
| 基金项目:国家自然科学基金资助项目(81172604/H2401) |
|
| 摘要点击次数: 1602 |
| 全文下载次数: 475 |
| 中文摘要: |
| 目的 分析菊叶三七(土三七)导致肝小静脉闭塞病(HVOD)的临床特点、诊治方法和预后。方法 回顾性分析35例因服用土三七所致肝小静脉阻塞病的临床资料。结果 HVOD临床表现为腹水(91%)、腹胀(86%)、纳差(71%)、乏力(71%)、肝肿大(66%)等。彩超可见肝大、腹水、肝内“豹纹状”、“斑片状”低回声区等,增强CT可见特征性“地图状”不均匀强化影。出院后随访1周至3年,失访3例,死亡13例,治愈/好转19例;死亡组病人白细胞计数、凝血酶原时间、血肌酐、尿素氮水平较治愈/好转组病人相对较高(P＜0.05)。结论 HVOD病程相对较短,诊治困难,预后较差。 |
| 英文摘要: |
| Objective To investigate the clinical characteristics,diagnosis,treatment and prognosis of hepatic veno-occlusive disease (HVOD) induced by gynura segetum.Methods A total of 35 HVOD patients induced by gynura segetum was retrospectively analyzed.Results The clinical symptoms of 35 HVOD patients included ascites (91%),abdominal dissension (86%),poor appetite (71%),feeble (71%),hepatom-egaly(66%).Image examination showed hepatomegaly,ascites and “leopard” or “patchy” low echo area in color doppler ultrasound,and characteristic “map” or “patchy” enhancement in enhanced computed tomography(CT).Followed up from one week to three years,3 cases were lost to follow-up,13 cases were died and 19 cases were cured or better.The prothrombin time (PT) was longer,and WBC,Scr and BUN were higher in dead patients than those in cured or better patients (P＜0.05).Conclusion The HVOD has short course,difficult diagnosis,limited treatment and poor prognosis. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
