| 周英,朱荣志,檀国祥,等.卒中前血糖水平对急性缺血性脑卒中早期神经功能缺损严重程度及预后的影响[J].安徽医药,2019,23(7):1437-1440. |
| 卒中前血糖水平对急性缺血性脑卒中早期神经功能缺损严重程度及预后的影响 |
| Effect of glucose before stroke on the severity of early neurological function and prognosis in patients with acute cerebral infarction |
| 投稿时间：2017-08-25 |
| DOI： |
| 中文关键词: 糖化血红蛋白 卒中 血糖 神经功能严重程度 预后 |
| 英文关键词: Glycosylated hemoglobin Stroke Blood glucose Severity of neurological function Prognosis |
| 基金项目: |
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| 摘要点击次数: 2026 |
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| 中文摘要: |
| 目的 探讨急性缺血性脑卒中前血糖水平对急性缺血性脑卒中病人早期神经功能缺损严重程度及预后的影响。方法 选取2016年1—7月铜陵市立医院神发病1周内住院的急性缺血性脑卒中病人90例,分析卒中前血糖水平与缺血性脑卒中急性期神经功能缺损的严重程度,观察卒中前血糖水平与病人入院时、出院时及出院90 d后卒中预后情况的关系。结果 90例中有29例诊断为糖尿病,其中23例卒中前有明确的糖尿病病史,6例为入院后诊断,在卒中前无明确糖尿病病史。糖化血红蛋白(HbA1c)升高组病人入院时空腹血糖水平明显高于HbA1c正常组病人(P=0.000)。90例中有25例(27.8%)入院时HbA1c＞6.4%,其中20例(占糖尿病病人的69.0%)糖尿病病人HbA1c升高,5例非糖尿病病人HbA1c升高。多因素分析显示HbA1c水平是美国国立卫生研究院卒中量表(NIHSS)评分的独立影响因素(P=0.013)；HbA1c水平(P=0.001)、既往卒中(P=0.016)是出院改良的Rankin量表(mRS)评分的独立影响因素；HbA1c水平(P＜0.001)是90 d mRS评分的独立影响因素。结论 不论病人是否存在糖尿病,卒中前的血糖水平与卒中严重程度相关,影响病人的预后。 |
| 英文摘要: |
| Objective To investigate the effect of Glucose before stroke on the severity of early neurological function and prognosis in patients with acute cerebral infarction.Methods A retrospective analysis,90 cases of the patients with acute ischemic stroke onset within one week were selected from January to July of 2016 in our hospital.The level of glucose before stroke and the extent degree in ischemic stroke acute stage were evaluated.The relationship between Glucose before stroke and neurological deficits in all patients at acute stage and the prognosis of the patients after stroke were analyzed. Results Among the 90 cases,29 cases were diagnosed as diabetes,of which 23 cases with diabetes history,6 cases were after hospitalization and with no significant symptom before die.The blood glucose levels of elevated hemoglobin group were significantly higher than those of the normal hemoglobin group before treatment(P=0.000).In this study,25 patients admitted(27.8%) had HbA1c＞6.4%,of which 20 patients with diabetes(69.0%) had increased HbA1c,and also HbA1c in 5 non\|diabetic patients had been increased.Multivariate analysis showed that HbA1c levels were independent predictors of NIHSS score,(P=0.013)；glycated hemoglobin levels(P=0.001) and history stroke(P=0.016) were the independent infuencing factors of discharge mRS score；glycated hemoglobin levels(P＜0.001),is the independent influencing factors of mRS score for 90 days.Conclusion Regardless of whether the patient is diabetic or not,pre-stroke blood glucose levels are associated with stroke severity,which affects the prognosis of the patient. |
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