| 张峰铭,金盛哲,葛春林.胆囊结石与遗传因素[J].安徽医药,2019,23(8):1492-1495. |
| 胆囊结石与遗传因素 |
| Gallstone and genetic factors |
| 投稿时间：2018-01-02 |
| DOI： |
| 中文关键词: 胆囊结石病 疾病遗传易感性 多态现象,遗传 胆固醇酯转运蛋白质类 受体,胆囊收缩素A 遗传 基因 |
| 英文关键词: Cholecystolithiasis Genetic predisposition to disease Polymorphism,genetic Cholesterol ester transfer proteins Receptor,cholecystokinin A Genetics Genes |
| 基金项目: |
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| 摘要点击次数: 2595 |
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| 中文摘要: |
| 胆囊结石是最常见的胆管疾病,也是最常见的消化道疾病之一。胆囊结石在发展中国家的发病率逐年提高,已经成为世界范围内第二常见的胃肠道疾病。流行病学研究提示,胆囊结石的形成与多种遗传因素和环境因素相关。人们通过连锁分析家系和种族研究探索遗传因素对胆囊结石形成起到的作用。越来越多的证据表明遗传因素对胆囊结石的形成起到了至关重要的作用。 |
| 英文摘要: |
| Gallstone disease is one of the most common biliary tract disorders worldwide and also one of the most common gastrointestinal disorders.The morbidity of gallstone disease is increasing with each passing year in developing countries and has become the second common gastrointestinal disorder.Epidemiologic studies have implicated that multiple environmental factors and genetic elements involve in gallstone formation.Genetic factors that influence gallstone formation have been elaborated from linkage studies,families,and ethnicities.Accumulating evidence indicates that genetic factors play an important role in gallstone disease. |
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