| 伍广伟,刘礼敬,王孟杰,等.封堵治疗卵圆孔未闭并发不同类型偏头痛47例[J].安徽医药,2019,23(9):1808-1811. |
| 封堵治疗卵圆孔未闭并发不同类型偏头痛47例 |
| Transcatheter closure of patent foramen ovale with cerebral infarction and migraine：47 cases |
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| DOI：10.3969/j.issn.1009-6469.2019.09.027 |
| 中文关键词: 卵圆孔未闭 偏头痛 心间隔封堵装置 经导管封堵 |
| 英文关键词: Patent foramen ovale Migraine Septal occluder device Transcatheter closure |
| 基金项目:广西壮族自治区科学技术厅科学研究与技术开发计划项目(桂科攻14124004-1-6) |
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| 中文摘要: |
| 目的 探讨封堵治疗卵圆孔未闭(PFO)并发不同类型偏头痛病人的临床疗效及安全性。方法 选取2013年1月至2016年1月在广西壮族自治区9家医院收治的PFO合并偏头痛病人47例，经PFO封堵治疗后，观察术前及术后头痛症状改变情况，C反应蛋白(CRP)、血浆一氧化氮(NO)水平及血液流变学指标血浆黏度(PV)、红细胞比容(Hct)的变化情况。结果 47例病人术后头痛影响测定-6(HIT-6)评分较术前有明显下降(P＜0.05)，经颅多谱勒超声发泡试验(c-TCD)声学造影检查仅2例存在Ⅱ级右向左分流；术后CRP、血浆NO水平及PV、Hct较术前有明显改善。结论 经导管封堵PFO是一种安全有效的治疗方法，可有效减少偏头痛的再发生。 |
| 英文摘要: |
| Objective To evaluate the therapeutic efficacy and safety of transcatheter closure of patent foramen ovale (PFO) with cerebral infarction and migraine.Methods 47 cases of patients with migraine in 9 hospital from Jan 2013 to Jan 2016 were enrolled.After treatment with line made plugging，the headache symptoms situation，c-reactive protein and plasma nitric oxide (NO) level and hemorheology indexes of plasma viscosity (PV)，hematocrit (Hct)，RBC’s changes were compared.Results Compared with before treatment，the HIT-6 were reduced significantly.Only 2 case exhibited 47 patients TCD and bubble test assessed the degree of shunting，including four cases of grade 2，All cases were successfully occluded，with the success rate of 100%，C-reactive protein，plasma nitric oxide (NO) level and blood rheology index plasma viscosity (PV) and erythrocyte ratio (Hct) indicators were significantly improved.Conclusion Transcatheter interventional occlusion of PFO is safe and effective in reducing recurrence of cerebral infarction and migraine. |
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