| 李娜,唐志红,田永明.2010—2018年某医院重症监护病房老年病人耐碳青霉烯鲍曼不动杆菌血流感染危险因素及预后分析[J].安徽医药,2020,24(5):903-907. |
| 2010—2018年某医院重症监护病房老年病人耐碳青霉烯鲍曼不动杆菌血流感染危险因素及预后分析 |
| Risk factors and prognosis of ICU elderly patieirts with carbapenem?resistant acinetobacter baumannii bloodstream infection in a hospital from 2010 to 2018 |
| |
| DOI：10.3969/j.issn.1009?6469.2020.05.014 |
| 中文关键词: 鲍氏不动杆菌 抗菌药 重症监护病房 老年人 耐碳青霉烯鲍曼不动杆菌 血流感染 危险因素 预后 |
| 英文关键词: Acinetobacter baumannii Anti?bacterial agents Intensive care units Aged Carbapenem?resistant acineto? bacter baumannii Bloodflow infection Risk factors Prognosis |
| 基金项目:四川省卫健委资助项目( 18PJ230) |
|
| 摘要点击次数: 1818 |
| 全文下载次数: 978 |
| 中文摘要: |
| 目的探讨重症监护病房( ICU)中老年病人耐碳青霉烯鲍曼不动杆菌( CRAB)血流感染危险因素及预后相关因素。方法回顾性收集 2010年 1月至 2018年 6月四川大学华西医院 ICU中 239例鲍曼不动杆菌血流感染老年病人的基本情况、疾病相关因素、侵入性操作相关因素、药物使用相关因素、辅助检查相关因素的病历资料。病例组为 157例 CRAB血流感染老年病人，对照组为同时期 82例碳青霉烯类敏感鲍曼不动杆菌( CSAB)血流感染老年病人，分析 CRAB血流感染的危险因素。并根据 30 d预后转归情况，将 239例老年病人进一步分为 114例预后良好组， 125例预后不良组，分析病人预后相关危险因素。结果多因素 logistic回归分析表明:运用碳青霉烯类抗生素、入院后感染前 ≥2种抗菌药物联用、深静脉置管、留置导尿管、是 CRAB血流感染老年病人的独立危险因素( P＜0.05)。影响鲍曼不动杆菌血流感染老年病人 30 d预后相关独立危险因素为: CRAB感染、入住 ICU时急性生理学及慢性健康状况评分系统( APACHⅡ)评分( P＜0.05)。结论运用碳青霉烯类抗生素、入院后感染前 ≥2种抗菌药物联用、深静脉置管、留置导尿管是 CRAB血流感染老年病人的危险因素， CRAB感染、入住 ICU时 APACHⅡ评分高提示老年病人预后差。 |
| 英文摘要: |
| Objective To explore the risk factors and prognostic factors of carbapenem?resistant Acinetobacter baumannii(CRAB) bloodstream infection in elderly patients in ICU.Methods A retrospective study was conducted on 239 elderly patients with Aci?netobacter baumannii bloodstream infections in ICU from January 2010 to June 2018.The following information was collected:the basic information，disease?related factors，invasive operation?related factors，drug use?related factors and auxiliary examination?relat?ed factors.The risk factors of CRAB bloodstream infection of 157 elderly patients with CRAB blood stream infection and 82 elderlypatients with carbapenem?sensitive Acinetobacter baumannii(CSAB)bloodstream infection in the control group were analyzed.Ac? cording to the prognosis of 30 days，239 elderly patients were further divided into 114 elderly patients with good prognosis groupand 125 elderly patients with poor prognosis group.The prognostic risk factors were analyzed.Results Multivariate Logistic regres? sion analysis showed that the carbapenems antibiotics，combined use of more than two kinds of antibiotics before infection after ad? mission，deep venous catheterization and indwelling catheter were independent risk factors for CRAB bloodstream infection in elder?ly patients(P＜0.05).The independent risk factors associated with 30 day prognosis of Acinetobacter baumannii bloodstream infec?tion in elderly patients were CRAB infection and APACHⅡ score at ICU admission(P＜0.05).Conclusion The use of carbapen? ems antibiotics，combined use of more than two kinds of antibiotics before infection after admission，deep vein catheterization andindwelling urethral catheter were risk factors for CRAB bloodstream infection in elderly patients.CRAB infection and high score ofAPACHⅡ when admitted to ICU indicated poor prognosis. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
