| 赵瑞婧,王丽娜,李娜苗,等.Meta分析法评价 CT引导下经皮肺穿刺活检对孤立性肺结节的诊断价值[J].安徽医药,2020,24(10):1909-1913. |
| Meta分析法评价 CT引导下经皮肺穿刺活检对孤立性肺结节的诊断价值 |
| Meta?analysis to evaluate the diagnostic value of CT?guided percutaneous lung biopsy for solitary pulmonary nodules |
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| DOI：10.3969/j.issn.1009?6469.2020.10.001 |
| 中文关键词: 孤立性肺结节/诊断 活组织检查，针吸 放射疗法，影像引导 体层摄影术， X线计算机 Meta分析 |
| 英文关键词: Solitary pulmonary nodule/diagnosis Biopsy,needle Radiotherapy,image?guided Tomography,X?ray comput? ed Meta?analysis |
| 基金项目:陕西省重点研发计划项目(2019SF?020) |
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| 中文摘要: |
| 目的用 Meta分析法综合评价 CT引导下经皮肺穿刺活检在鉴别孤立性肺结节(Solitary Pulmonary Nodules，SPNs)良恶性的诊断价值。方法系统搜索 Medline、PubMed、VIP、中国期刊全文数据库(CNKI)和万方医学网等数据库，检索时间截至 2019年 3月，检索使用 CT引导下经皮肺穿刺活检诊断 SPNs的相关中外文献，按照 Cochrane协作网推荐的诊断试验纳入标准筛选文献，提取纳入研究文献的特征信息。文献评价采用诊断研究评价工具 QUADAS，Meta分析采用 Stata15.1软件进行。结果共纳入 12篇研究文献，共计 1 053例病人。汇总计算特异度、灵敏度、阳性似然比、阴性似然比和诊断比值比，绘制汇总受试者工作特征(SROC)曲线并计算曲线下面积(AUC)以及 95%CI，分别为 0.99(0.85～1.00)0.95(0.90～0.98)91.5(5.70～1 460.50)，0.05(0.02～0.10)，1 921(117.00～31 666.00)、 0.99(0，.98～1.00).结论 CT引导下经皮肺，穿刺活检应用于肺，部 SPNs的诊断，具有较高的特异度、灵敏度以及准确率，是肺部 SPNs的一项重要诊断方法，具有较高诊断效能。 |
| 英文摘要: |
| Objective To comprehensive evaluate the diagnosis value of CT?guided percutaneous lung biopsy in the identificationof solitary pulmonary nodules(SPNs)of benign and malignant with a Meta?analysis.Methods Relevant English and Chinese liter?atureson CT?guided percutaneous lung biopsy to diagnose SPNs were searched in the Medline，PubMed，VIP，CNKI and WAN? FANG databases，with retrieval time until March 2019.According to the inclusion criteria recommended by the Cochrane MethodsGroup on Screening and Diagnostic Tests，，the literatures were screened and the characteristic information of the included research? es was extracted.The literature evaluation was performed using the diagnostic research evaluation tool QUADAS，and Meta?analysis was performed using Stata 15.1.Results A total of 12 studies were included，with a total of 1053 patients.The specificity，sensitivi? ty，positive likelihood ratio，negative likelihood ratio and diagnostic ratio were calculated，and the SROC curves were drawn and the area under the curve and the 95%CI were calculated as0.99(0.85～1.00)，0.95(0.90～0.98)91.5(5.7～1 460.5)，0.05(0.02～0.10)1 921(117～31 666.00)、 0.99(0.98～1.00)，respectively.Conclusion taneous lung biopsy has been ap? CT?guidedpercu，pliedto，the diagnosis of pulmonary SPNs with high specificity，sensitivity and accuracy，and is an important diagnostic method of pulmonary SPNs with high diagnostic efficiency. |
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