| 王靖秋,陆晓媛,经莉.加速康复外科对腹腔镜全子宫切除术病人围手术期免疫功能的影响[J].安徽医药,2020,24(10):1982-1985. |
| 加速康复外科对腹腔镜全子宫切除术病人围手术期免疫功能的影响 |
| Effect of enhanced recovery after surgery on perioperative immune function in patients undergoing gynecological laparoscopic total hysterectomy |
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| DOI：10.3969/j.issn.1009?6469.2020.10.016 |
| 中文关键词: 子宫切除术/护理 腹腔镜检查 加速康复外科 围手术期 免疫球蛋白类 CD4阳性 T淋巴细胞 |
| 英文关键词: Hysterectomy/ nursing Laparoscopy Enhanced recovery after surgery(ERAS) Perioperative period Immuno?globulins CD4?positive T?lymphocytes |
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| 中文摘要: |
| 目的研究加速康复外科理念对腹腔镜全子宫切除术病人围手术期免疫功能的影响。方法选取 2019年 2—7月在徐州医科大学附属医院妇科行腹腔镜下全子宫切除术的病人 90例，用抽签法分为两组，一组为加速康复外科组(45例)围手术期予加速康复外科管理模式，一组为常规组(45例)围手术期予传统管理模式。结果两组病人术后第 1天免疫球蛋，白 M(IgM)、免疫球蛋白 G(IgG)、免疫球蛋白 A(IgA)水平均较，术前降低， ERAS组术后第 1天免疫球蛋白指标明显高于对照组［IgA为(1.876±0.665)比(1.623±0.483)g/L，IgG为((9.158±1.029)比(8.441±1.052)g/L，IgM为(1.091±0.319)比(0.919±0.382)g/L，均 P＜0.05］；两组术后第 3天 lgG的水平均较术后第 1天升高， ERAS组术后第 3天 IgG明显高于对照组［(10.422±1.117)比(9.876±1.205)g/L，P＜0.05］；两组病人术后第 1天及术后第 3天 T淋巴细胞总数(CD3+)、辅助性 T细胞(CD4+)、 CD4+/CD8+均先下降后升高， ERAS组术后第 1天 CD3+、CD4+、CD4+/CD8+明显高于对照组［(61.178±6.046)%比(58.533±5.168)%，(34.844±5.321)%比(28.222±5.257)%，(1.981±0.969)%比(1.635±0.595)%，均 P＜0.05］。结论在妇科行腹腔镜全子宫切除手术的病人中，加速康复外科围手术期管理模式可以降低免疫抑制，促进病人的康复。 |
| 英文摘要: |
| Objective To study the effect of enhanced recovery after surgery(ERAS)on perioperative immune function of gyneco? logical laparoscopic surgery patients.Methods Ninety cases of patients who underwent total laparoscopic hysterectomy in gynecolo?gy department of Affiliated Hospital of Xuzhou Medical University from February 2019 to July 2019 were selected and randomly di?vided into two groups by lottery:ERAS group(45 cases)，which underwent perioperative fast track surgery management mode，and the conventional group(45 cases)，which underwent traditional management mode.Results The IgA，IgG and IgM levels of pa? tients on the 1st day after surgeryin both groups were all lower than those before surgery .The IgA，IgGand IgM were significantly higher in ERAS group than those in the control group on the 1st day after surgery［(1.876±0.665)vs.(1.623±0.483)g/L，(9.158± 1.029)vs.(8.441±1.052)g/L，(1.091±0.319)vs.0.919±0.382)g/L，all P＜0.05］.IgG levels in both groups were higher on the 3rdday after surgery than those on the 1st day after surgery.ERAS group had significantly higher IgGon the 3rd day after surgery thanthe control group［(10.422±1.117)vs.(9.876±1.205)g/L)，P＜0.05］.The total number of T lymphocytes(CD3+)，helper T cells(CD4+)and CD4+/CD8+ decreased first and then increased in both groups on the 1st and 3rd day after surgery.The total number of CD3+，CD4+，CD4+/CD8+cells in the ERAS groupwas significantly higher than that of the control group，［(61.178±6.046)%vs. |
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