| 姚翀,张超学.组织声学结构定量技术在酒精性肝纤维化诊断中的应用[J].安徽医药,2020,24(11):2150-2152. |
| 组织声学结构定量技术在酒精性肝纤维化诊断中的应用 |
| Application of tissue acoustic structure quantitative technique in the diagnosis of alcoholic liver fibrosis |
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| DOI：10.3969/j.issn.1009?6469.2020.11.008 |
| 中文关键词: 肝硬化 肝炎，酒精性 超声检查 组织声学结构定量 酒精性肝纤维化 |
| 英文关键词: Liver cirrhosis Hepatitis,alcoholic Ultrasonography Acoustic structure quantification technology Alcoholic liver fibrosis |
| 基金项目:安徽省自然科学基金项目(1708085MH205) |
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| 中文摘要: |
| 目的探讨组织声学结构定量技术(ASQ)在酒精性肝纤维化诊断中的应用。方法选取 2017年 7月至 2018年 6月安徽医科大学第一附属医院住院经肝活检确诊的酒精性肝纤维化病人 51例，为观察组；选取同期体检的健康志愿者 37例，为健康对照组。两组均采用 ASQ检测肝脏，获得 χ2直方图和相关参数，包括红色和蓝色曲线的标准差值、平均值、众数值和蓝红色曲线下的面积比值。结果与对照组相比，观察组的红色曲线分布变宽，不平滑，峰值明显大于 100%，蓝色曲线下面积显著增加，峰值和宽度均显著增加。观察组红色曲线的标准差值、红色曲线的众数值、红色曲线的平均值、蓝色曲线的众数值、蓝色曲线的平均值和蓝红色曲线下的面积比值显著大于健康对照组，差异有统计学意义(P＜0.01)。结论 ASQ技术可以通过无创和客观的参数成像为酒精性肝纤维化的诊断提供依据。 |
| 英文摘要: |
| Objective To explore the application of tissue acoustic structure quantitative technique(ASQ)in the diagnosis of alco? holic liver fibrosis.Methods Fifty?one patients with alcoholic liver fibrosis confirmed by liver biopsy in the first Affiliated Hospi?tal of Anhui Medical University from July 2017 to June 2018 were selected as the experimental group，and 37 healthy volunteers were selected as the control group.Both groups underwent ASQ for liver examination and the χ2 histogram and related parameters were obtained，including the mean，mode，standard deviation and area ratio under the blue?red curve.Results Compared with the control group，the distribution of the red curve in the experimental group became wider，uneven，and the peak value was more than 100%.The area under the blue curve increased significantly，and the peak value and width increased significantly.The red curve mode，red curve mean，standard deviation of red curve，blue curve mode，blue curve mean，and area ratio under the blue?red curve of the experimental group were significantly larger than those of the control group，and the difference was statistically significant(P＜0.01).Conclusion ASQ technology can provide a basis for the diagnosis of alcoholic liver fibrosis by non?invasive and objec? tive parametric imaging. |
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