文章摘要
邹敏超,袁风红,陈海凤,等.重症系统性红斑狼疮心肌累及 2例报告及文献复习[J].安徽医药,2020,24(12):2373-2376.
重症系统性红斑狼疮心肌累及 2例报告及文献复习
Myocardial involvement in two patients with severe systemic lupus erythematosus:case report and literature review
  
DOI:10.3969/j.issn.1009?6469.2020.12.011
中文关键词: 红斑狼疮,系统性  心肌疾病  心肌累及  吗替麦考酚酯
英文关键词: Lupus erythematosus,systemic  Cardiomyopathies  Myocardial involvement  Mycophenolate mofetil
基金项目:国家自然科学青年基金(81501345)
作者单位E-mail
邹敏超 南京医科大学附属无锡人民医院风湿免疫科江苏无锡 214023  
袁风红 南京医科大学附属无锡人民医院风湿免疫科江苏无锡 214023 cyjyfh@126.com 
陈海凤 南京医科大学附属无锡人民医院风湿免疫科江苏无锡 214023  
刘婷 南京医科大学附属无锡人民医院风湿免疫科江苏无锡 214023  
高恺言 南京医科大学附属无锡人民医院风湿免疫科江苏无锡 214023  
胥魏 南京医科大学附属无锡人民医院风湿免疫科江苏无锡 214023  
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中文摘要:
      目的探讨重症系统性红斑狼疮(SLE)心肌累及的诊治经验。方法纳入南京医科大学附属无锡人民医院 2015年 11月收住的 2例重症 SLE心肌累及的病人,分析其临床表现、实验室结果、辅助检查、治疗过程及预后。结果 2例病人出现了心电图、超声心动图(UCG)异常, 1例病人同时出现心肌酶异常。糖皮质激素联合吗替麦考酚酯治疗病情缓解。结论联合心电图、 UCG、心肌酶谱检查有助于 SLE心肌损害的诊断及疗效监测,糖皮质激素联合吗替麦考酚酯治疗 SLE心肌累及有效。
英文摘要:
      Objective To investigate the diagnosis and treatment of myocardial involvement in patients with severe systemic lupus er? ythematosus(SLE).Methods Two patients with SLE myocardial involvement admitted by The Affiliated Wuxi People’s Hospital of Nanjing Medical University in November 2015 were included,and clinical manifestations,laboratory results,auxiliary examina? tions,treatment process and prognosis were analyzed.Results Two patients presented with abnormal electrocardiogram and ultra? sonic cardiogram(UCG),and one patient presented with abnormal myocardial enzyme.Patients with glucocorticoid combined with mycophenolate mofetil were in remission.Conclusion Combined electrocardiogram,UCG and myocardial enzyme profile is helpful for the diagnosis and efficacy monitoring of SLE myocardial damage,and glucocorticoid combined with mycophenolate mofetil is ef? fective in the treatment of SLE myocardial involvement.
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