| 张近,程颢,管延红,等.高频超声检查诊断甲状腺乳头状癌微钙化的价值分析[J].安徽医药,2020,24(12):2494-2498. |
| 高频超声检查诊断甲状腺乳头状癌微钙化的价值分析 |
| Value of high frequency ultrasound in the diagnosis of microcalcification in papillary thyroid carcinoma |
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| DOI：10.3969/j.issn.1009?6469.2020.12.040 |
| 中文关键词: 甲状腺肿瘤 超声检查，多普勒 癌，乳头状 钙化微粒 诊断 病理特征 |
| 英文关键词: Thyroid neoplasms Ultrasonography,doppler Carcinoma,papillary Calcifying nanoparticles Diagnosis Pathological features |
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| 中文摘要: |
| 目的分析 17 MHz高频超声诊断甲状腺乳头状癌微钙化的价值。方法选取 2016年 2月至 2018年 5月在西安市第九医院就诊的 163例甲状腺乳头状癌病人为研究对象。所有病人均接受常规超声及 17 MHz高频超声检查。观察并记录甲状腺乳头状癌病人甲状腺结节的部位、边界、内部回声、后方回声等。采用受试者工作特征曲线(ROC)分析 17 MHz高频超声诊断甲状腺乳头状癌微钙化的价值。分析甲状腺乳头状癌微钙化与甲状腺乳头状癌病人临床病理的关系。结果病理检查证实 163例甲状腺乳头状癌病人中 28例伴微钙化， 135例不伴微钙化。 17 MHz高频超声对甲状腺乳头状癌微钙化的检出率为 92.86%(26/28)，明显高于常规超声的 67.86%(19/28)，差异有统计学意义(P＜0.05)。 17 MHz高频超声诊断甲状腺乳头状癌微钙化 ROC曲线下面积(AUC)、灵敏度、特异度、符合率分别为 0.930(0.904～0.978)、 92.86%、90.37%、90.80%。17 MHz高频超声在诊断深度＜ 2.6 cm的甲状腺癌微钙化符合率约为 94.39%，而在诊断深度 ≥2.6 cm的甲状腺癌微钙化符合率为 83.93%。甲状腺乳头状癌微钙化病人的甲状腺包膜受侵犯及淋巴结转移比例增高。结论 17 MHz高频超声对甲状腺乳头状癌微钙化的检出率高于常规超声，甲状腺乳头状癌微钙化与不良病理特征有关。 |
| 英文摘要: |
| Objective To analyze the value of 17 MHz high frequency ultrasound in the diagnosis of microcalcification in papillary thyroid carcinoma.Methods A total of 163 cases of papillary thyroid cancer patients treated in The Ninth Hospital of Xi’an from February 2016 to May 2018 were selected as the research subjects.All patients were examined by conventional ultrasound and 17MHz high frequency ultrasound.The location，boundary，internal echo and posterior echo of thyroid nodules in patients with papil?lary thyroid cancer were observed and recorded.The value of 17 MHz high frequency ultrasound in the diagnosis of microcalcifica?tion in thyroid papillary carcinoma was analyzed by receiver operating characteristic(ROC)curve.The relationship between micro?calcification in papillary thyroid carcinoma and clinical pathology of papillary thyroid carcinoma was analyzed.Results Pathologi?cal examination confirmed that 28 of 163 cases of papillary thyroid cancer were accompanied by microcalcification and 135 caseswere not accompanied by microcalcification.The detection rate of microcalcification in thyroid papillary carcinoma by 17 MHz highfrequency ultrasound was 92.86%(26/28)，which was significantly higher than that by conventional ultrasound(67.86%，19/28)， with statistical significance(P＜0.05).The area under the ROC curve(AUC)，sensitivity，specificity and coincidence rate of 17MHz high?frequency ultrasound in the diagnosis of microcalcification of papillary thyroid carcinoma were 0.930(0.904-0.978)， |
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