文章摘要
刘丽云,付丽彬,邹红.除湿解毒足浴汤洗剂联合萘替芬酮康唑乳膏治疗浸渍糜烂型足癣 40例[J].安徽医药,2021,25(2):400-403.
除湿解毒足浴汤洗剂联合萘替芬酮康唑乳膏治疗浸渍糜烂型足癣 40例
Observation on the clinical effects made by Chushijiedu foot bath decoction lotion combined with naftifine hydrochloride and ketoconazole cream on treating impregnated erosive tinea pedis: 40 cases
  
DOI:10.3969/j.issn.1009-6469.2021.02.046.
中文关键词: 脚癣  除湿解毒足浴汤  临床疗效
英文关键词: Tinea pedis  Chushijiedu foot bath decoction lotion  Clinical effects
基金项目:
作者单位
刘丽云 达州市中西医结合医院皮肤科四川达州 635000 
付丽彬 达州市中西医结合医院皮肤科四川达州 635000 
邹红 达州市中西医结合医院皮肤科四川达州 635000 
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中文摘要:
      目的观察除湿解毒足浴汤洗剂联合萘替芬酮康唑乳膏治疗浸渍糜烂型足癣的临床效果。方法选取 2014年 7月至 2016年 6月达州市中西医结合医院门诊确诊的浸渍糜烂型足癣病人 80例,按随机数字表法分为观察组和对照组,每组各 40例。对照组用温开水泡足晾干后予以萘替芬酮康唑乳膏外擦治疗;试验组用除湿解毒足浴汤洗剂泡足晾干后给予萘替芬酮康唑乳膏外擦治疗。治疗 2周时分别观察两组病人的不良反应、临床疗效,同时观察 80%病人治愈所需的疗程、首次治愈后再次复发的时间及 3年内的复发次数。结果治疗 2周后,两组病人不良反应差异无统计学意义( P > 0.05)观察组治愈率高于对照组(62.5%比 40.0%,P < 0.05);观察组 80%病人治愈所需疗程显著低于对照组[(18.2±3.8)d比( 25.7±5.5)d,,P < 0.05];首次治愈后,观察组病人首次复发的时间显著迟于对照组[(1.5±0.7)年比( 1.0±0.4)年, P < 0.05],3年内观察组复发次数显著低于对照组[( 1.9±1.1)次比( 2.8±0.9)次, P < 0.05]。结论除湿解毒足浴汤洗剂联合萘替芬酮康唑乳膏治疗浸渍糜烂型足癣安全有效。
英文摘要:
      Objective To evaluate the clinical effects of Chushijiedu foot bath decoction lotion combined with naftifine hydrochloride and ketoconazole cream in treating impregnated erosive tinea pedis.Methods Eighty patients with impregnated tinea pedis diagnosed in the outpatient department of Dazhou Integrated Traditional Chinese and Western Medicine Hospital from July 2014 to June2016 were assigned into 2 groups randomly. The control group with 40 cases was treated with naftifine hydrochloride and ketoconazolecream after drying with Normal temperature boiling water external bubble, while the experimental group with 40 cases was treated withnaftifine hydrochloride and ketoconazole cream after drying with Chushijiedu foot bath decoction lotion. After 2 weeks of treatment,the adverse reactions and clinical effects of the two groups were observed respectively, and the cure rate of 80% of the patients was observed at the same time.Course of treatment, the time of recurrence after the first cure and the number of recurrence within three years.Results After 2 weeks of treatment, there was no significant difference in adverse reactions between the two groups (P ≥ 0.05), the clinical efficacy of the experimental group was significantly better than that of the control group(62.5% vs. 40.0%, P < 0.05), the courseof treatment of 80% of the patients in the experimental group was significantly lower than that of the control group [(18.2±3.8)d vs. (25.7±5.5)d, P < 0.05], the recurrence time of the experimental group was significantly later than that of the control group [(1.5±0.7) vs. (1.0±0.4), P < 0.05], and the recurrence frequency of the experimental group was significantly lower than that of the control group within three years [(1.9±1.1) vs. (2.8±0.9), P < 0.05].Conclusion Chushijiedu foot bath decoction lotion combined with naftifine hydrochloride and ketoconazole cream is safe and effective in the treatment of impregnated erosive tinea pedis.
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