文章摘要
刘思婷,单鸣秋,郭书臣.市售天麻饮片 6种活性成分与抗氧化活性的相关性研究[J].安徽医药,2021,25(5):874-878.
市售天麻饮片 6种活性成分与抗氧化活性的相关性研究
Study on the correlation between 6 active contents and antioxidant activity of Gastrodiae Rhizoma
  
DOI:10.3969/j.issn.1009-6469.2021.05.007
中文关键词: 天麻属  主成分分析  高效液相色谱  1,1-二苯 -2-苦基肼  活性成分  抗氧化活性
英文关键词: Gastrodia  Principal component analysis  HPLC  DPPH  Active contents  Antioxidant activity
基金项目:
作者单位
刘思婷 南京医科大学附属儿童医院江苏南京210008 
单鸣秋 南京中医药大学、江苏省中药资源产业化过程协同创新中心江苏南京 210023 
郭书臣 南京中医药大学、江苏省中药资源产业化过程协同创新中心江苏南京 210023 
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中文摘要:
      目的考察天麻 6种活性成分(天麻素、对羟基苯甲醇、香荚兰醇、巴利森苷 A、巴利森苷 B、巴利森苷 C)与抗氧化活性的相关性。方法采用高效液相色谱( HPLC)法测定天麻饮片中 6种活性成分的含量;以 1,1-二苯 -2-苦基肼( DPPH)作为指标,采用 HPLC法评价天麻饮片的抗氧化活性;利用 EXCEL进行线性拟合,以相关系数评价活性成分与抗氧化活性的相关性。结果 6种活性成分 1种或 6种总含量与天麻 DPPH清除率的线性相关系数均在 0.0~0.2之间。结论天麻 6种活性成分与天麻抗氧化活性无明显相关性,可能存在其他有效清除自由基的成分,或者天麻的抗氧化活性可能是多种活性成分的协同作用。
英文摘要:
      Objective To evaluate the correlation between 6 active contents (gastrodin, p-hydroxybenzaldehyde, vanillin,, parishin A, parishin B, parishin C) and antioxidant activity of Gastrodiae Rhizoma.Methods (1) The contents of 6 active components of Gastro? diae Rhizoma were detected by HPLC.(2) The antioxidant activity of Gastrodiae Rhizoma was evaluated by HPLC with DPPH as indicator. (3) The relationship between 6 active contents and antioxidant activity of Gastrodiae Rhizoma was evaluated by excel.Results The correlation coefficients between 1 or 6 active contents of Gastrodiae Rhizoma and scavenging rates of DPPH free radical by Gastrodiae Rhizoma were among 0.0-0.2.Conclusion There is no significant correlation between 6 active contents and antioxidant activity of Gas? trodiae Rhizoma. Antioxidant activity of Gastrodiae Rhizoma might be caused by other active contents, otherwise, the synergistic effect of several active contents.
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