| 苍姗,张转运,荣辉.脊柱手术部位感染病原菌特征及危险因素调查分析[J].安徽医药,2021,25(5):879-882. |
| 脊柱手术部位感染病原菌特征及危险因素调查分析 |
| Pathogenic bacteria characteristics and risk factors investigation and analysis of surgical site infection after spinal surgery |
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| DOI：10.3969/j.issn.1009-6469.2021.05.008 |
| 中文关键词: 外科伤口感染 手术后并发症 脊柱手术 手术部位 感染 病原菌 危险因素 |
| 英文关键词: Surgical wound infection Postoperative complications Spinal surgery Surgical site Infection Pathogenic bacteria Risk factor |
| 基金项目:国家自然科学基金( 81901136) |
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| 摘要点击次数: 1345 |
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| 中文摘要: |
| 目的调查分析脊柱手术术后手术部位感染病原菌特征及危险因素。方法选取 2017年 8月至 2019年 8月在南京鼓楼医院进行脊柱手术病人 5 021例，回顾性分析所有病人临床资料，并对相关资料进行单因素分析及多因素分析。结果 5021例病人术后手术部位感染 31例( 0.62%)，共分离出 41株病原菌，革兰阳性菌 25株( 61.0%)，革兰阴性菌 16株( 39.0%)。单因素分析结果显示感染与未感染病人年龄，体质量指数(BMI)值，糖尿病率，手术时间，术中失血量，手术入路及内固定率差异有统计学意义( P<0.05)。 Logistic多因素分析结果显示年龄，糖尿病，手术时间，术中失血量及内固定为脊柱手术部位感染的危险因素(P<0.05)。结论脊柱手术术后手术部位感染病原菌主要以金黄色葡萄球菌，表皮葡萄球菌及大肠埃希菌等为主。病人年龄， BMI值，糖尿病率，手术时间，术中失血量，手术入路及内固定为手术部位感染独立危险因素。同时对于有相关因素的病人需加强预防，以降低手术部位感染发生率。 |
| 英文摘要: |
| Objective To investigate and analyze the pathogenic bacteria characteristics and risk factors of surgical site infection after spinal surgery.Methods 5021 patients treated with spinal surgery in Nanjing Drum Tower hospital from August 2017 to August2019 were collected and analyzed by univariate analysis and Logistic multivariable analysis.Results 20 cases had surgical site infection after spinal surgery(0.62%). Totally 41 strains of pathogens were cultured and isolated, including 25 strains of gram-positive bacteria(61.0%), and 18 strains of gram-negative bacteria(39.0%). Univariate analysis results showed that age, BMI index, diabetes, operation time, blood loss in operation, surgical approaches and internal fixation had significantly difference between uninfected patients andinfected patients(P<0.05). Logistic multivariable analysis results showed that age, diabetes, operation time, blood loss in operation andinternal fixation were risk factors(P<0.05).Conclusions The Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coliare the major bacteria in surgical site infection after spinal surgery. Age,BMI value,diabetes, operation time, blood loss in operation andinternal fixation were risk factors. At the same time, it is necessary to strengthen the prevention of patients with related factors to reducethe incidence rate of surgical site infection after spinal surgery |
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