| 代天,杨萍,黎明.介入联合早期心脏康复治疗老年急性心肌梗死并高血压 90例分析[J].安徽医药,2021,25(6):1162-1165. |
| 介入联合早期心脏康复治疗老年急性心肌梗死并高血压 90例分析 |
| Interventional therapy combined with early cardiac rehabilitation for elderly patients with acute myocardial infarction complicated with hypertension: an analysis of 90 cases |
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| DOI：10.3969/j.issn.1009-6469.2021.06.025 |
| 中文关键词: 心肌梗死 高血压 经皮冠状动脉介入治疗 心脏康复 早期医疗干预 心脏功能 不良事件 |
| 英文关键词: Myocardial infarction Hypertension Percutaneous coronary intervention Cardiac rehabilitation Early medical intervention Cardiac function Adverse events |
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| 中文摘要: |
| 目的急性心肌梗死并高血压老年病人应用介入与早期心脏康复联合干预治疗效果、心脏功能与不良事件情况分析。方法选取 2018年 1月至 2019年 1月武汉市第六医院诊治 180例急性心肌梗死并高血压老年病人资料，按随机数字表法分为两组，各 90例。对照组予以介入与常规康复干预，研究组予以介入与早期心脏康复联合干预，均直到半年。分析两组临床疗效、心脏功能、血清相关指标与不良事件情况。结果治疗后，研究组临床总有效 96.67%比对照组( 85.56%)高( P<0.01)；研究组室壁运动积分指数( WMSI)(1.34±0.41)比对照组( 1.98±0.38)低，研究组左心室射血分数( LVEF(70.20±7.85)%比对照组(62.07±8.93)%高( P<0.01)；且研究组一氧化氮( 96.88±8.32)μmol/L比对照组( 82.85±8.65)μmol/L高；研究组肿瘤坏死因子 α(TNF-α)(4.23±0.82)μg/L、ET-1(内皮素 -1)(3.32±0.79)μg/L均比对照组( 5.68±1.22)μg/L、(4.56±0.84)μg/L少( P<0.01)；研究组发生心力衰竭 2.22%、心绞痛 2.22%等不良事件比对照组 13.33%、14.44%等低( P<0.01)。结论急性心肌梗死并高血压老年病人应用介入与早期心脏康复联合方案，能有效改善病人心脏功能及血清相关指标，提高临床疗效，并降低不良事件发生，具一定临床应用价值。 |
| 英文摘要: |
| Objective To analyze the effect of interventional therapy combined with early cardiac rehabilitation in the treatment ofelderly patients with acute myocardial infarction complicated with hypertension and its effects on cardiac function and adverse events.Methods The clinical data of 180 elderly patients with acute myocardial infarction complicated with hypertension who had been diagnosed in The Affiliated Hospital of Jianghan University from January 2018 to January 2019 were selected. The patients were assignedinto two groups according to the random number table, with 90 cases in each group. The control group was given intervention and routine rehabilitation, whereas the study group was given interventional therapy combined with early cardiac rehabilitation for half a year.The clinical efficacy, cardiac function, serum-related indicators and adverse events in the two groups were compared.Results After treatment, the total response rate in the study group was 96.67%, higher than that in the control group (85.56%, P<0.01). The wall motion score index (WMSI) in the study group was lower than that in the control group [(1.34±0.41) vs. (1.98±0.38)], and left ventricular ejection fraction (LVEF) in the study group was higher than that in the control group [(70.20±7.85)% vs. (62.07±8.93)%, P<0.01]. Thenitric oxide (NO) in the study group was higher than that in the control group [(96.88±8.32) μmol/L vs. (82.85±8.65) μmol/L], and thetumor necrosis factor α (TNF-α) and endothelin-1 (ET-1) in the study group were lower than those in the control group [ (4.23±0.82)μg/ L vs. (5.68±1.22) μg/L, (3.32±0.79)μg/L vs.(4.56±0.84) μg/L, respectively; P<0.01]. The incidences of heart failure and angina pectoris in the study group were lower than those in the control group (2.22% vs. 13.33%, 2.22% vs. 14.44%, respectively; P<0.01).Conclu? sion For elderly patients with acute myocardial infarction complicated with hypertension, interventional therapy combined with earlycardiac rehabilitation can effectively improve their cardiac function and serum-related indicators, increase the clinical efficacy and reduce adverse events, which is of certain clinical value. |
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