| 易勤,刘超群,黄亮.神经梅毒致麻痹性痴呆 3例[J].安徽医药,2021,25(6):1177-1179. |
| 神经梅毒致麻痹性痴呆 3例 |
| Paralytic dementia caused by neurosyphilis in 3 cases |
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| DOI：10.3969/j.issn.1009-6469.2021.06.029 |
| 中文关键词: 神经梅毒 痴呆 青霉素 G 精神异常 |
| 英文关键词: Neurosyphilis Dementia Penicillin G Mental disorders |
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| 中文摘要: |
| 目的总结 3例由神经梅毒导致的麻痹性痴呆病人的诊治过程，积累该类病人的临床诊疗经验。方法回顾性分析 2018年 7月至 2019年 7月入住株洲市中心医院的神经梅毒所致的麻痹性痴呆病人 3例的临床资料，探讨其临床表现和治疗手段。结果 3例临床表现为精神行为异常的麻痹性痴呆病人，在分别给予青霉素钠 320万 U，每 8小时 1次，同时予以恩替卡韦片 0.5 mg每天 1次；苄星青霉素 240万 U，每周 1次及头孢曲松 2g每天 1次的抗病毒治疗后，临床症状皆有所改善。结论加强临床医务人员对麻痹性痴呆的临床表现多样化的认识，及早鉴别诊断并治疗，对麻痹性痴呆病人的预后有重要的临床意义。 |
| 英文摘要: |
| Objective To summarize the diagnosis and treatment process of 3 cases of paralytic dementia caused by neurosyphilis,and to accumulate the clinical diagnosis and treatment experience of such patients. Methods Three cases of paralytic dementiacaused by neurosyphilis admitted to Zhuzhou Central Hospital from July 2018 to July 2019 were retrospectively analyzed, and theirclinical manifestations and treatment methods were discussed.Results The treatment three patients with paralytic dementia with abnormal mental behavior were given 3.2 million U of penicillin sodium (once every 8 hours), 0.5 mg of entecavir tablets (once a day), andantiviral treatment for 2.4 million U of benzylpenicillin (once a week) combined with 2 g of ceftriaxone (once a day), the clinical symp toms have improved.Conclusion It is possible to strengthen the understanding of the clinical manifestations of paralytic dementiaamong the medical staff and make early differential diagnosis and treatment, which is of great clinical significance for the prognosis ofpatients with paralytic dementia. |
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