| 白雪松,李长辉,袁硕,等.通腑泄浊法治疗危重病病人胃肠功能障碍 60例临床观察[J].安徽医药,2021,25(7):1328-1331. |
| 通腑泄浊法治疗危重病病人胃肠功能障碍 60例临床观察 |
| Clinical observation on 60 cases of critically ill patients with gastrointestinal dysfunction in application of Tongfu Xiezhuo treatment |
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| DOI：10.3969/j.issn.1009-6469.2021.07.013 |
| 中文关键词: 危重病人医疗 胃肠疾病 植物药疗法 通腑泄浊法 胃肠功能障碍 APACHEⅡ评分 C反应蛋白 |
| 英文关键词: Critical care Gastrointestinal diseases Phytotherapy Tongfu Xiezhuo Gastrointestinal dysfunction The score of APACHE Ⅱ C-reactive protein |
| 基金项目:辽宁省科技厅发展计划处( 2017010008-301)；周学文国医大师传承工作室(辽宁中医药大学涵字［2018］76号) |
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| 中文摘要: |
| 目的观察通腑泄浊法治疗危重病病人胃肠功能障碍临床疗效。方法 2015年 1月至 2018年 1月于辽宁中医药大学附属医院住院并发生胃肠功能障碍的 120例病人，按住院的先后顺序，按照事先由随机数确定的随机分组方法，进入观察组和对照组。观察组在西药治疗原发病基础上，加用通腑泄浊中药治疗。比较两组有效率、死亡率、 APACHE Ⅱ评分、 C反应蛋白水平。结果观察组有效率为86.67%(52/60)，对照组为 71.67%(43/60)，观察组较对照组高( P<0.05)；而观察组死亡率为 18.33%(11/ 60)对照组为 35.00%(21/60)，观察组死亡率低于对照组( P<0.05)。观察组治疗前 APACHE Ⅱ评分( 23.08±7.64)治疗后为(11.79±4.13)，对照组治疗前 APACHE Ⅱ评分(22.15±8.36)治疗后为(14.76±4.81)，两组 APACHE Ⅱ评分治疗后均明显下降(P<0.05)观察组较对照组下降更明显(P<0.05)。观察组治疗C反应蛋白水平(102.87±37.06)治疗后(41.79±14.07)，对照组治疗前，前C反应，蛋白水平(105.64±38.35)，治疗后 C反应蛋白水平(72.86±13.74)，两组 C反应蛋白水平治疗后均明显下降(P<0.05)，观察组较对照组下降更明显(P<0.05)。结论 应用通腑泄浊法治疗危重病人胃肠功能障碍有效。 |
| 英文摘要: |
| Objective To observe the clinicalefficacy of Tongfu Xiezhuo in treating gastrointestinal dysfunction in critically illpatients. Methods One hundred and twenty critically ill patients with gastrointestinal dysfunction who were hospitalized in the Intensive CareUnit of Affiliated Hospital of Liaoning University of Traditional Chinese Medicine were selected and randomly assigned into observationgroup and control group according to the order of hospitalization and the random grouping method determined by the random number atfirst. The observation group was given Tongfu Xiezhuo traditional Chinese medicine on the basis of the treatment of underlying disease bywestern medicine. The effective rate, mortality, the score of APACHE Ⅱ and the level of C-reactive protein were compared between two groups.Results The effective rate of the treatment observation group was 86.67% (52/60), the effective rate of the control group was71.67% (43/60), the observation group was higher than the control group (P<0.05), and the mortality rate of the observation group was18.33% (11/60), the mortality rate of the control group was 35.00% (21/60), and the mortality rate of the observation group was lower thanthat of the control group (P<0.05). The intra-abdominal pressure classification of the observation group before treatment was statisticallysignificant. The APACHE Ⅱ score before treatment in the observation group was (23.08±7.64), after treatment was (11.79±4.13), beforetreatment in the controlgroup was (22.15±8.36) ,and after treatment was (14.76±4.81), the APACHE Ⅱ scores ofthe two groups decreasedsignificantly after treatment (P<0.05), in the observation group decreased more significantly than that in the control group (P≤0.05). The level of C-reactive protein before treatment in the observation group was (102.87±37.06), the level of C-reactive protein after treatment was (41.79±14.07), the level of C-reactive protein before treatment in the control group was (105.64±38.35), and the level of C-reactive protein after treatment was (72.86±13.74) , the C-reactive protein levels of the two groups decreased significantly after treatment (P<0.05), and the C-reactive protein level in the observation group decreased more significantlythan that in the control group (P<0.05).Conclusion It is effective totreatgastrointestinaldy sfunction incritically illpatientswiththemethodofdredgingthefu-organsandreleasingthetur bidity. |
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