| 张晓莉,于泓,韩冬梅,等.泪道 U形置管术联合地塞米松注射液冲洗治疗泪道阻塞 40例[J].安徽医药,2021,25(8):1663-1666. |
| 泪道 U形置管术联合地塞米松注射液冲洗治疗泪道阻塞 40例 |
| Lacrimal duct U-shaped catheterization combined with dexamethasone in treating 40 cases of lacrimal duct obstruction |
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| DOI：10.3969/j.issn.1009-6469.2021.08.044 |
| 中文关键词: 泪器阻塞 泪道 U形置管 地塞米松 鼻泪管 临床效果 安全性 |
| 英文关键词: Lacrimal duct obstruction Lacrimal duct U-shaped tube Dexamethasone Nasolacrimal duct Clinical effect Safety |
| 基金项目:廊坊市科技支撑计划项目( 2015013005C) |
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| 中文摘要: |
| 目的探讨泪道 U形置管联合地塞米松治疗泪道阻塞的临床效果及安全性。方法选取 2017年 1月至 2018年 1月在廊坊市人民医院就诊的泪道阻塞病人 80例( 104眼)，采用随机数字表法分为联合组(泪道 U形置管联合地塞米松注射液治疗)和对照组(泪道 U形置管治疗)各 40例，对比两组治疗前后不同时间点泪液分泌量、泪膜破裂时间及两组临床疗效、并发症率。结果联合组和对照组的泪液分泌量治疗前［(14.4±2.7)mm/5min比( 15.0±2.4)mm/5min］、治疗 1个月后［( 19.2±3.1)mm/5min比( 20.0±3.5)mm/5min］比较，差异无统计学意义( P>0.05)；拔管后，联合组的泪液分泌量低于对照组［( 11.3±2.7)mm/5min比 |
| 英文摘要: |
| Objective To investigate the clinical effect and safety of lacrimal duct U-shaped tube combined with dexamethasone in the treatment of lacrimal duct obstruction.Methods Eighty patients (104 eyes) who were treated in the People's Hospital of Langfangform January 2017 to January 2018 were selected as the research object, and they were assigned into the combined group (lacrimal ductU-tube combined with dexamethasone treatment) and the control group (lacrimal duct U-shaped tube), with 40 cases in each group. Thedifference of tear secretion, tear film rupture time, clinical efficacy difference and complication rate between the two groups of patients atdifferent time points before and after treatment were compared.Results The tear secretion in the combined group and the control group before treatment [(14.4±2.7) mm/5min vs. (15.0±2.4) mm/5min] and after 1 month of treatment [(19.2±3.1) mm/5min vs. (20.0±3.5) mm/5min] was detected, and there was no statistically significant difference. After extubation, the tear secretion in the combined group waslower than that in the control group[(11.3±2.7) mm/5min vs. (13.2±2.5) mm/5min, P<0.05], and the tear secretion after extubation in both groups was lower than before treatment (P<0.05). Before treatment, 1 month after treatment, and after extubation, the tear film rupturetime of the combined group and the control group was compared between the two groups and at different time points, and there was no statistically significant difference (P> 0.05). After treatment, the recovery rate of the combined group was 76.92%, the improvement rate was23.08%, the control group was 53.85%, the improvement rate was 44.23%, and the inefficiency was 1.92%. The clinical efficacy of thecombination group was better than the control group (P<0.05). During treatment, the complication rate of the combined group (3.85%) was lower than 19.23% of the control group (P <0.05).Conclusion The lacrimal duct U-shaped tube combined with dexamethasone is better than lacrimal duct U-shaped tube alone in treating lacrimal duct obstruction,and has the advantage of reducing complications. |
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