| 张瑞芳,常红娟,薛松梅.儿童弱视 158例综合治疗的阶段性疗效分析[J].安徽医药,2021,25(9):1822-1825. |
| 儿童弱视 158例综合治疗的阶段性疗效分析 |
| Analysis of phased effect of comprehensive therapy on amblyopia in 158 children |
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| DOI：10.3969/j.issn.1009-6469.2021.09.029 |
| 中文关键词: 弱视 眼防护装置 阶段性治疗 屈光矫正 遮盖治疗 弱视训练 疗效 |
| 英文关键词: Amblyopia Eye protective devices Stage treatment Direfractive correction Occlusion treatment Amblyopia training Efficacy |
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| 中文摘要: |
| 目的探讨综合疗法对不同年龄、不同程度儿童弱视阶段性疗效的影响。方法选取 2019年 2—5月新乡医学院第三附属医院眼科门诊就诊的弱视儿童 158例，给予综合治疗，即将屈光矫正、遮盖治疗、弱视训练、药物治疗相结合，以 3个月为 1个治疗阶段，共 4个阶段，即 T1 ~ T4，记录各治疗阶段后的矫正视力情况。结果 158例病儿各阶段复诊时的矫正视力进步行数在不断提高(均 P < 0.01)。经过 12个月的综合治疗， T1、T2、T3、T4阶段有效率( 26.78%、63.29%、86.71%、91.77%)，T3与 T2、T4与 T3阶段疗效差异有统计学意义(均 P < 0.001)。病人按照年龄分为幼儿期、学龄前期、学龄期，在 T1、T2阶段，不同年龄组的疗效差异无统计学意义(均 P > 0.05)； T3、T4阶段，不同年龄组的疗效差异有统计学意义(均 P < 0.05)，疗效与年龄负相关，年龄越大，疗效越差( rs=?0.164，P <0.05；rs=?0.180，P< 0.05)。病人按照弱视程度分为轻度、中度和重度组， T1、T2阶段，不同弱视程度组的疗效差异无统计学意义(均 P>0.05)T3、T4阶段，不同弱视程度组的疗效差异有统计学意义(均 P<0.05)，且疗效与弱视程度负相关，程度越重，疗效越差( rs=?0.201，P，< 0.05；rs=?0.304，P<0.05)。结论儿童弱视治疗是一个长期的过程，不同治疗阶段矫正视力提高行数并非均匀一致的提高，但各阶段进步行数及治疗效果随治疗时间的延长而提高，且疗效与病儿年龄、弱视程度负相关。 |
| 英文摘要: |
| Objective To investigate the effect of comprehensive therapy on children with different ages and degrees of amblyopia. Methods From February to May 2019, 158 children with amblyopia in the Ophthalmology Clinic of the Third Affiliated Hospital ofXinxiang Medical University were selected and received a comprehensive treatment, that is, refractive correction, occlusion treatment,amblyopia training and drug treatment. The overall treatment time was equally divided into four stages, sequentially named T1 -T4, and each phase lasted 3 months. After each treatment stage, the corrected visual acuity of each children was recorded.Results The corrected visual acuity of 158 children in each stage was elevated after 12 months of comprehensive treatment and there were statistically significant differences among each stage (all P < 0.01). The effective rate of stage T1, T2, T3, and T4 was 26.58%, 63.29%, 86.71%,and 91.77%, respectively. There were statistically significant differences from T3 and T2, T4 and T3 (all P < 0.001). The patients were divided into early childhood, pre-school childhood and school-age childhood by age. There was no significant difference in the efficacyof amblyopia among different age groups in the stage T1 and T2. For T3 and T4 stages, there were significant differences in the efficacyof amblyopia among different age groups (all P < 0.05). Meanwhile, the efficacy was negatively correlated with age (rs = ?0.164, P < 0.05; rs = ?0.180, P < 0.05). The patients were divided into mild group, moderate group and severe amblyopia group according to the degree of amblyopia. In T1 and T2 stages, there was no significant difference in the efficacy of amblyopia among different amblyopiagroups (P > 0.05). For T3 and T4 stages, there were significant differences (all P < 0.05), and the therapeutic effect was negatively correlated with the degrees of amblyopia (rs = ?0.201, P < 0.05; rs = ?0.304, P < 0.05).Conclusions The treatment of amblyopia in children is a long-term process. The corrected visual acuity of each stage is elevated with the extension of curative time, though the improvement of corrected visual acuity of different treatment phases is not completely consistent. The curative effect is negatively correlated with the ages of children and the degrees of amblyopia. |
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