| 陈益家,贾妙柱,唐佳佳.止痛如神汤加减联合吻合器痔上黏膜环切术治疗痔疮 48例[J].安徽医药,2022,26(2):334-337. |
| 止痛如神汤加减联合吻合器痔上黏膜环切术治疗痔疮 48例 |
| Effects of Zhitong Rushen decoction combined with procedure for prolapse and hemorrhoids on hemorrhoid:48 cases |
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| DOI：10.3969/j.issn.1009-6469.2022.02.030 |
| 中文关键词: 痔 痔切除术 止痛如神汤 吻合器痔上黏膜环切术 中医证候积分 血清超敏 C反应蛋白 疼痛数字评价量表 |
| 英文关键词: Hemorrhoids Hemorrhoidectomy Zhitong Rushen decoction Procedure for prolapse and hemorrhoids TCM syn. drome score Serum hypersensitive C-reactive protein Numerical rating scale |
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| 中文摘要: |
| 目的探讨止痛如神汤加减联合吻合器痔上黏膜环切术( PPH)对痔疮病人中医证候积分、血清超敏 C反应蛋白( CRP)水平及疼痛数字评价量表( NRS)评分的影响。方法选取 2018年 1月至 2019年 10月绵阳市中医医院收治的 96例痔疮病人作为研究对象，采用随机数字表法分为对照组和观察组，各 48例。两组病人均接受 PPH手术治疗，术后接受 1∶5 000高锰酸钾温水坐浴。在此基础上，对照组同时服用西药地奥司明片；观察组服用止痛如神汤加减治疗。比较两组治疗前后炎症因子水平、 NRS评分、肛肠动力学指标、中医证候积分。结果与治疗前相比，治疗后两组病人的炎症因子水平、 NRS评分、中医证候积分均降低(P<0.05)；观察组病人的肛肠动力学指标:肛管最大收缩压(MSP)高压区长度(HPZ)、直肠静息压(RRP)、直肠最大耐受容量( MTV)、直肠肛管抑制反射阈值( AIRT)与治疗前相比，差异无统计学意、义( P>0.05)，对照组病人的 MSP、HPZ及 MTV水平较治疗前降低， RRP及 AIRT水平较治疗前升高(P<0.05)。与治疗后对照组相比，治疗后观察组病人的炎症因子水平、 NRS评分［( 1.20±0.26)分比( 2.94±0.49)分］、中医证候积分、 RRP［( 6.53±1.05)mmHg比( 7.85±0.99)mmHg］及 AIRT［( 24.32±6.23)mL比 |
| 英文摘要: |
| Objective To explore the effect of Zhitong Rushen decoction combined with procedure for prolapse and hemorrhoids (PPH) on the TCM syndrome score, serum hypersensitive C-reactive protein (CRP) level and numerical rating scale (NRS) score of hemor. rhoids patients.Methods Ninety-six patients with hemorrhoids admitted to Mianyang Hospital of Traditional Chinese Medicine fromJanuary 2018 to October 2019 were selected as the study objects, and they were assigned into control group and observation group accord.ing to the random number table method, with 48 cases in each group. The patients in both groups were treated with PPH and 1:5000 warmwater bath with potassium permanganate after operation. On this basis, the control group took the western medicine Diosmin tablets at thesame time; the observation group used the addition and subtraction of Zhitong Rushen decoction. The level of inflammatory factors, NRSscore, anorectal dynamic index and TCM symptom score were compared between the two groups before and after treatment.Results Compared with before treatment, the levels of inflammatory factors, NRS scores and TCM syndrome scores of the two groups were de.creased (P < 0.05); there was no significant difference in the anorectal motility indexes: maximum anal systolic pressure (MSP), high pres.sure zone length (HPZ), rectal resting pressure (RRP), maximum rectal tolerance volume (MTV), and anorectal inhibitory reflex threshold(AIRT) of the observation group compared with those before treatment (P > 0.05), the levels of MSP, HPZ and MTV in the control groupwere lower than those before treatment, and the levels of RRP and AIRT were higher than those before treatment (P < 0.05). Compared with the control group after treatment, the level of inflammatory factors, NRS score [(1.20±0.26) score vs. (2.94±0.49) score], TCM symp. tom score, levels of RRP [(6.53±1.05) mmHg vs. (7.85±0.99) mmHg] and AIRT [(24.32±6.23) mL vs. (32.73±6.02) mL] in the observation group after treatment were lower, and MSP [(129.97±24.47) mmHg vs. (117.76±26.28) mmHg], HPZ [(3.57±0.79) cm vs. (2.68±0.72) cm] and MTV [(199.29±27.17) mL vs. (175.49±31.67) mL] were higher (P < 0.05).Conclusion Zhitong Rushen decoction combined with procedure for prolapse and hemorrhoids is more effective than diosmin tablets combined with procedure for prolapse and hemorrhoids inreducing the TCM symptom score, serum hs-CRP level and NRS score, and help to improve the clinical symptoms of patients. |
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