| 郭丹丹,柏雪,张鹏,等.路易体痴呆 14例的临床分析[J].安徽医药,2022,26(6):1141-1143. |
| 路易体痴呆 14例的临床分析 |
| Lewy body dementia: a clinical analysis of 14 cases |
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| DOI：10.3969/j.issn.1009-6469.2022.06.018 |
| 中文关键词: 痴呆 认知功能障碍 锥体外束 脑缺血 Lewy体病 路易体痴呆 诊断 |
| 英文关键词: Dementia Cognitive dysfunction Extrapyramidal tracts Brain ischemia Lewy body disease Dementia with Lewy body Diagnose |
| 基金项目: |
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| 中文摘要: |
| 目的探讨路易体痴呆病人的临床特征。方法对 2015年 1月至 2019年 5月在山西省人民医院诊断的 14例路易体痴呆病人的临床资料进行回顾性分析。结果 14例病人中男性 9例( 64.3%)女性 5例( 35.7%)年龄范围为 55~83岁。首发 |
| 英文摘要: |
| Objective To explore the clinical characteristics of patients with Lewy body dementia.Methods A retrospective analysis was made of the clinical data of 14 patients with Lewy body dementia diagnosed in Shanxi People's Hospital from January 2015 toMay 2019.Results Among the 14 patients, there were 9 males (64.3%) and 5 females (35.7%), aged between 55 and 83 years old. Initial symptoms included visual hallucinations (7.1%), , symptoms of Parkinson's disease (42.9%) and cognitive impairment (57.1%). Asfor the clinical manifestations, all the 14 patients had cognitive impairment, of whom 64.3% showed a fluctuation of cognitive impairment, 86% had Parkinson's symptoms and 79% had visual hallucinations. Among the supportive symptoms, 14% had autonomic nervous dysfunction, 93% had mental symptoms, and MRI results of all the 14 patients showed cerebral ischemia or brain atrophy. At theend of follow-up, 8 patients were bedridden, 4 patients were in stable condition, and 2 patients died.Conclusions Lewy body dementia usually occurs after the age of 50, with fluctuating cognitive impairment, visual hallucination and Parkinson-like symptoms as initialmanifestation. Its progress is rapid, and there is no specific manifestation found in magnetic resonance imaging. At present, there is stillno effective drug therapy, so symptomatic support treatment is mainly used. |
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