| 徐勤鸿,周立京,张毓萍,等.术前雾化吸入布地奈德、特布他林对老年腹部手术病人术前肺功能及术后肺部并发症的影响[J].安徽医药,2022,26(6):1171-1174. |
| 术前雾化吸入布地奈德、特布他林对老年腹部手术病人术前肺功能及术后肺部并发症的影响 |
| Effect of preoperative atomization inhalation on preoperative pulmonary function improvement and postoperative pulmonary complications in elderly patients undergoing abdominal surgery |
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| DOI：10.3969/j.issn.1009-6469.2022.06.026 |
| 中文关键词: 投药，吸入 围手术期医护 外科手术 腹部 布地奈德 特布他林 老年人 手术后并发症 |
| 英文关键词: Administration, inhalation Perioperative care Surgical procedures, operative Abdomen Budesonide Terbutaline Elderly patients Postoperative complications |
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| 中文摘要: |
| 目的探讨术前雾化吸入布地奈德、特布他林对老年腹部手术病人术前肺功能改善情况及术后肺部并发症发生的影响。方法对 2019年 1—12月间入住西安交通大学第一附属医院 120例行腹部外科手术老年病人通过随机数字表法分为对照组及试验组，每组 60例，入院后常规进行肺通气功能检查，试验组病人术前常规给予雾化吸入(布地奈德混悬液 1.0毫克 /次+硫酸特布他林雾化液 5.0毫克 /次+生理盐水 20毫升 /次，每天 3次) +常规呼吸功能锻炼，对照组仅进行常规呼吸功能锻炼， 3 d后再次评估病人肺功能改善情况；术后两组病人常规均进行雾化吸入，雾化方式同前，并对比两组病人术后肺部并发症发生及临床相关指标情况。结果试验组及对照组经过雾化吸入或呼吸功能锻炼后术前肺功能均有明显改善，但试验组病人肺功能改善率为 80%(48/60)较对照组 50%(30/60)更为明显( P=0.001)；术后试验组病人肺部并发症发生率为 8.3%(5/60)，明显低于对照组 23.3%(14/60)(P=0.024)；术后试验组使用雾化吸入治疗时间为( 4.3±1.1)d明显少于对照组( 6.2±1.5)d(P<0.001)；另外试验组病人术后住院天数为( 8.1±3.4)d明显低于对照组( 10.4±3.4)d(P<0.001)。结论术前雾化吸入布地奈德、特布他林能够明显改善老年腹部手术病人术前肺功能，并能够减少术后雾化吸入时间，降低术后肺部并发症发生及缩短术后住院时间。 |
| 英文摘要: |
| Objective To investigate the effect of preoperative atomization inhalation (budesonide suspension combined with terbutaline sulfate atomization) on the improvement of preoperative pulmonary function and postoperative pulmonary complications in elderly patients undergoing abdominal surgery.Methods A total of 120 elderly patients admitted to Department of Geriatric Surgery, FirstAffiliated Hospital of Xi'an Jiaotong Universityfor abdominal surgery from January to December 2019 were randomly assigned into control group and experiment group, 60 patients in each group in accordance with the random number table. After admission, all the patients were given routine pulmonary ventilation test. Before operation, the patients in the experiment group were given routine atomization inhalation (budesonide 1.0 mg/time + terbutaline 5.0 mg/time + normal saline 20 mL/time, three times a day) plus routine respiration functional exercise. However, the control group only carried out routine respiratory function exercise, and the improvement of pulmonary function was evaluated again 3 days later. After the operation, the patients in both two groups routinely conducted atomizationinhalationin the same way as that before the operation, and the incidence of postoperative pulmonary complications and clinical indicators of the two groups were compared.Results The pulmonary functions of patients in both the experiment group and the control groupimproved significantly after inhalation or respiratory exercise, but the improvement rate of the pulmonary function of the experimentgroup was 80% (48/60) which was higher than that of the control group [50% (30/60)]; the difference was statistically significant (P= 0.001). The incidence of pulmonary complications of the experiment group was 8.3% (5/60), which was significantly lower than that ofthe control group [23.3% (14/60)]; the difference was statistically significance (P = 0.024). After operation, the treatment time of atomization inhalation in the experiment group was (4.3 ± 1.1) d, which was significantly shorter than that in the control group (6.2 ± 1.5) d;the difference was statistically significant (P<0.001). In addition, the hospital stay in the experiment group was (8.1±3.4) d, which wasshorter than that in the control group (10.4±3.4) d; which was statistically significant (P<0.001).Conclusion Preoperative atomizationinhalation of can significantly improve the preoperative pulmonary function of elderly patients undergoing abdominal surgery, and candecrease the postoperative atomization inhalation time, reduce the postoperative pulmonary complications and shorten the postoperative hospital stay. |
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