| 钟志强,曾繁增,朱蔷,等.完全腹膜外腹腔镜疝修补术与开放疝修补术对腹股沟斜疝老年病人术后应激、免疫功能及近期生活质量的影响[J].安徽医药,2022,26(12):2474-2479. |
| 完全腹膜外腹腔镜疝修补术与开放疝修补术对腹股沟斜疝老年病人术后应激、免疫功能及近期生活质量的影响 |
| Effects of total extraperitoneal herniorrhaphy and open hernioplasty on stress, immune function and short-term quality of life in elderly patients with indirect inguinal hernia |
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| DOI：10.3969/j.issn.1009-6469.2022.12.031 |
| 中文关键词: 疝，腹股沟 完全腹膜外腹腔镜疝修补术 开放疝修补术 应激 免疫功能 生活质量 老年人 |
| 英文关键词: Hernia, inguinal Total extraperitoneal laparoscopic hernia repair Open hernia repair Stress Immune func. tion Quality of life Aged |
| 基金项目:梅州市社会发展科技计划项目( 181229162051576) |
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| 中文摘要: |
| 目的研究完全腹膜外腹腔镜疝修补术( TEP)与开放疝修补术对腹股沟斜疝老年病人术后应激、免疫功能及近期生活质量的影响。方法采用便利抽样法选取 2019年 3—12月梅州市第三人民医院腹股沟斜疝病人 92例，采用 TEP病人 51例为观察组、开放疝修补术病人 41例为对照组。观察两组病人术中情况、术后恢复情况，术前、术后 24 h和术后 72 h时应激水平、免疫功能变化及术后 1个月生活质量。结果两组病人均顺利完成手术，对照组手术时间短于观察组［(41.64±7.22)min比(59.43±11.91)min］观察组术后尿管拔除时间、下床活动时间及住院时间均少于对照组［( 9.21±2.43)h比( 15.62±3.94)h，(6.42±2.73)h比( 11±4.24)h，(5.74±1.32)d比( 6.42±1.75)d］，术后并发症发生率低于对照组( 1.96%比 14.63%)，均差异有统计学意义( P<0.05)。时间因素对两组病人皮质醇、肾上腺素、去甲肾上腺素(NA)及 CD4阳性 T淋巴细胞( CD4+)、 CD8阳性 T淋巴细胞( CD8+)、 CD4+/CD8+肾上腺素、 ［观察组:95，的影响均差异有统计学意义( P<0.05)。两组术后 24 h时皮质醇、NA及 CD8+(155.58±24.31)μg/L、(2.60±0.53)μg/L、(3.94±0.79)μg/L、(27.14±3.92)%，对照组:(158.35±26.56)μg/L、(2.63±0.51)μg/L、(3.99±0.81)μg/L、(27.92±3.15)%］均明显高于术前［观察组:(98.25±31.23)μg/L、(2.29±0.44)μg/L、(3.43±0.74)μg/L、(21.82±2.60)%，对照组:(97.55±32.35)μg/L、(2.27±0.42)μg/L、(3.40±0.71)μg/L、(21.90±3.31)%］、术后 72 h［观察组:(99.80±29.16)μg/ L、(2.31±0.42)μg/L、(3.44±0.72)μg/L、(22.07±2.90)%，对照组:(101.27±29.58)μg/L、(2.32±0.44)μg/L、(3.46±0.74)μg/L、 |
| 英文摘要: |
| Objective To study the effects of total extraperitoneal herniorrhaphy (TEP) and open hernioplasty on stress, immunity and short-term quality of life in elderly patients with indirect inguinal hernia. Methods A total of 92 patients with indirect inguinalhernia undergoing surgery in the Third People's Hospital of Meizhou from March to December 2019 were selected by convenience sam.pling method, and 51 TEP patients were used as observation group and 41 patients control group. An observation was made of the intra.operative and postoperative conditions of the patients. The changes of stress level, immune function and quality of life in one monthwere observed before operation, 24 hours after operation and 72 hours after operation. Results Both groups successfully completedthe operation. The operation time of the control group was shorter than that of the observation group [(41.64±7.22) min vs. (59.43± |
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